Settra/sitafloxacin

@payette78 If I recall correctly, you are about to be treated for Mycobacteria Abscessus. That is a really tough infection, and resistant to most of the usual antibiotics. M Abscessus is also one of the fastest growing and potentially life-threatening of the mycobacteria. In most cases, it NEEDS to be treated, the sooner the better.

It looks like there is a new tool, sitafloxacin, in the arsenal:
https://pmc.ncbi.nlm.nih.gov/articles/PMC8770805/
And here is a very recent article detailing its successful use:
https://assets.cureus.com/uploads/case_report/pdf/331025/20250218-551765-2xh0eo.pdf
Now, I will tell you every drug in this class, the fluoroquinolones, has a chance of serious side effects. That does not mean every patient using them will react, or that the reactions cannot be managed if that is needed. Like many therapies (think chemo) risks of treatment need to be balanced against the seriousness of the infection.

What information did you gat from your recent appointmant?

@payette78 If I recall correctly, you are about to be treated for Mycobacteria Abscessus. That is a really tough infection, and resistant to most of the usual antibiotics. M Abscessus is also one of the fastest growing and potentially life-threatening of the mycobacteria. In most cases, it NEEDS to be treated, the sooner the better.

It looks like there is a new tool, sitafloxacin, in the arsenal:
https://pmc.ncbi.nlm.nih.gov/articles/PMC8770805/
And here is a very recent article detailing its successful use:
https://assets.cureus.com/uploads/case_report/pdf/331025/20250218-551765-2xh0eo.pdf
Now, I will tell you every drug in this class, the fluoroquinolones, has a chance of serious side effects. That does not mean every patient using them will react, or that the reactions cannot be managed if that is needed. Like many therapies (think chemo) risks of treatment need to be balanced against the seriousness of the infection.

What information did you gat from your recent appointmant?

@payette78 If I recall correctly, you are about to be treated for Mycobacteria Abscessus. That is a really tough infection, and resistant to most of the usual antibiotics. M Abscessus is also one of the fastest growing and potentially life-threatening of the mycobacteria. In most cases, it NEEDS to be treated, the sooner the better.

It looks like there is a new tool, sitafloxacin, in the arsenal:
https://pmc.ncbi.nlm.nih.gov/articles/PMC8770805/
And here is a very recent article detailing its successful use:
https://assets.cureus.com/uploads/case_report/pdf/331025/20250218-551765-2xh0eo.pdf
Now, I will tell you every drug in this class, the fluoroquinolones, has a chance of serious side effects. That does not mean every patient using them will react, or that the reactions cannot be managed if that is needed. Like many therapies (think chemo) risks of treatment need to be balanced against the seriousness of the infection.

What information did you gat from your recent appointmant?

@payette78 If I recall correctly, you are about to be treated for Mycobacteria Abscessus. That is a really tough infection, and resistant to most of the usual antibiotics. M Abscessus is also one of the fastest growing and potentially life-threatening of the mycobacteria. In most cases, it NEEDS to be treated, the sooner the better.

It looks like there is a new tool, sitafloxacin, in the arsenal:
https://pmc.ncbi.nlm.nih.gov/articles/PMC8770805/
And here is a very recent article detailing its successful use:
https://assets.cureus.com/uploads/case_report/pdf/331025/20250218-551765-2xh0eo.pdf
Now, I will tell you every drug in this class, the fluoroquinolones, has a chance of serious side effects. That does not mean every patient using them will react, or that the reactions cannot be managed if that is needed. Like many therapies (think chemo) risks of treatment need to be balanced against the seriousness of the infection.

What information did you gat from your recent appointmant?

I think if my ID doc doesn't understand inducible resistance i am in trouble. I am going to insist on waiting on the clarithromycin inducible results but am i overreacting to doubt her expertise? Maybe she just didn't want to explain inducible resistance (which i understand perfectly well). She knows i do a lot of research on my own as my way of coping.

Yes, a lot of times it feels like we know things the doctors don't expect when dealing with our rare situations. Hopefully, she is someone you can easily talk to about your concerns.