Sertraline and arrythmia

Selective Serotonin reuptake inhibitors (SSRIs) are common antidepressants. Sertraline (Zoloft) helps raise the neurotransmitter serotonin in the brain to help calm anxiety, promote sleep and improve mood. Neurotransmitters are chemical messengers that help transmit nerve impulses, and deficiencies in the neurotransmitters are associated with depression/anxiety. Uncommonly, a side effect called serotonin syndrome (SS) occurs which can cause arrhythmia, tachycardia, sweating, nausea, vomiting, restlessness or agitation. This SS can occur at normal doses and with any drug that affects serotonin levels. It’s uncommon and usually subsides within 24 hrs if drug is stopped. An antihistamine, cyproheptadine, can be prescribed as an antidote for severe cases. The benefits of sertraline can be substantial and the risk of SS is low. The risk of untreated depression is high. I hope this sheds light on your question and you can read about neurotransmitters and SS online.