Second opinion for husband's stage 4A prostate cancer? And update

Posted by cheriekhan @cheriekhan, May 14, 2024

My partner was diagnosed with stage 4 A prostate cancer with spread to pelvic lymph nodes. Oncologist has recommended surgery followed by radiation and hormone therapy for a good prognosis. He is 65 healthy and no symptoms. PSA was 11. Has a history of prostrate cancer. Was wondering if we should get another opinion regarding getting surgery first. The dr wants to treat it aggressively. Any advice on what to expect, next steps appreciated.

More Information: Hi father died of prostrate cancer as did his uncle. His Gleason score was 9. And all 12 pieces of the biopsies had cancer: Prostatic adenocarcinoma, Grade Group 5 (Gleason score 4+5=9), involving 100%, 100%, 90%, 90%, 90%, and 80% (15 mm, 14 mm, 14 mm, 14 mm, 14 mm, 5 mm) of 6/6 cores. PSMA pet scan results: Intense PSMA uptake in the prostrate gland from apex to base.No psma avid osseous metastases. Non puma avid low attenuation bilateral adrenal nodule are indeterminant. Recommend dedicated contrast imaging for further evaluation. They did genetic testing waiting for results. This is being done at Cornell Weil in Manhattan with experts in the field.

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@robertmizek

I’m on Orgovyx and Zytiga as well; going on 5 months. As long as I exercise each day the side effects aren’t too bad.

I’ve had IMRT. Not sorry I chose it, but have wondered if I would’ve had less side effects with proton therapy. A consult with a radiologist specializing in each might be helpful in making a decision.

Since my situation is so similar to that of your partners, don’t hesitate to send me a direct private message if there’s anything I can help you with or you have any questions Did you think I might be able to answer from my experience.

Bob

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I had SBRT, which is somewhere in-between IMRT and Proton in terms of precision.

Despite some side effects, in retrospect I have no regrets about getting radiation therapy that affected a wider area — the less precise it is, the more likely it will catch something they missed.

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