Looking for research re: taking AI drugs vs not taking them
I am currently taking Exemestane. I’m 61. Took a while but I’m doing well on it (doing yoga, pranayama and acupuncture). I now have osteopenia after taking it six months. I’m trying to find research on taking AIs vs not taking. What I’m finding there is not much difference between taking and not taking. But more likely to get arthritis and osteoporosis.
Can anyone post links. .
Interested in more discussions like this? Go to the Breast Cancer Support Group.
I would also love to see research on taking AIs or not. Having been through diagnosis, lumpectomy, stage one a, 7MM, single foci, ER positive PR positive HER2 negative, I made the personal decision to have radiation only. I am 68 and I'm choosing quality of life over the apparent small decrease AIs will provide to recurrence risk. My genetic risk factor is extremely low as well. It's a risk but one I am willing to take. I would not make this decision if I was not so early stage with all the right indicators of low risk of recurrence. It's such a tough decision.
There is research out there. Ask your doctors to give you specific studies with dates when they were completed to discuss the pros and cons. Not everybody can take an aroma taste inhibitor for a variety of reasons. It’s difficult to read the medical jargon for the average patient, but you can ask your oncologist to explain to you the pros and cons, depending upon your type of cancer, how your odds of survival improve or not with the use of an AI medication. In my case, with ER positive and PR positive breast cancer taking an AI inhibitor lowers my risk for a recurrence of breast cancer. Doesn’t lower it by 100%, but it is done all or nothing decision. My breast cancer team and my oncology team are the best sources I have found for information on issues like this. There is no one-size-fits-all out there. But depending upon your type of cancer and a host of other variables, they should be able to give you some indication of where your risk of recurrence will be if you can take an AI versus what your risk would be if you do not take an AI. The date in the five years I have been a breast cancer. Patient is increased significantly so what might’ve been a recommendation five years ago may not be the recommendation they would currently give.