Reclast - Please share your positive experiences

I truly feel for anyone suffering from these drugs and sincerely hope you get relief soon. The only way I would use ReClast is if I could receive a smaller dosage instead of infusing mega quantities into my body.

I strongly encourage those suffering from adverse effects to report them.
"You may report side effects to FDA at 1-800-FDA-1088." You can also report them on-line via MedWatch, I believe.

Have any of you suggested to your dr that you take a 6 month dose of Reclast, with a reduced dose? Instead of the 12 month infusion. It is a very powerful drug and being so it seems to be the best one after prolia discontinuance. Also the infusion should take longer than 15 mins. That is far too short a time with this drug.

I agree with Victor.

This paper shows that half dose is as effective as full dose and lasts a year. That can be monitored with CTX analysis to determine when the next infusion would be warranted.

Thanks for the link, @normahorn. I hope those who are considering a lower dose of reclast bring a copy of the pdf to their doctor's appointments. If successful in getting a low dose reclast, please share CTX changes and therapy outcome.

For those who are going to use reclast after prolia cessation, a low dose reclast might need extra monitoring as the timing and magnitude of CTX increase will be unpredictable.

I am a 73 year old healthy woman. I was diagnosed with osteoporosis thru dexa scan. I had Reclast in December 2024. Except for feeling tired day after infusion, I had no other side effects. I took tylenol day before, day of, and day after infusion. I also drank 64 oz. of water day before, day of, and day after. I still try to drink as much water as I can to protect my kidneys. My next Reclast will be in December of 2025.

It may be early to know if the lower dose will provide lasting bone density. This paper states that while there was an increase in bone density on the lower dose it is unknown whether it will have lasting effect. It would be awesome if it does! The study was only for one year, though.

I think the current belief is that the higher dose, maybe even given in multiple lower dose sessions, is what is needed to give the 3-5 year (minimum) benefit. I don’t know if my insurance will pay for multiple lower doses because it is charged as a hospital visit - which is always incredibly expensive. Even if the infusion is given at a clinic or infusion center, those facilities usually bill like a hospital visit- something to do with the quality of care/facility that qualifies them as a “hospital”.

I’m going to ask my endocrinologist before this upcoming infusion. I did ask the cancer enter rheumatologist (who is co-provider for my bone issues) about delaying the third infusion and he stated that it needs to be given three years in a row.

I will risk your concerns to escape being overdosed with a toxic substance by the one-size-fits-all mind set that exists. This atuff stays in one's body for something like 10 years.

CTX analysis meaning? Thank you.

I had my first reclast infusion in Oct . 2024 after a year on Evenity. I drank water constantly the day before, the day after, and I continue to drink water daily. I took one or 2 Tylenol proactively. I had no problem with the infusion, but I still worry about the long term side effects down the road.