Reaction to switching prednisone to hydrocortisone

They usually switch to hydrocortisone for those that will be on corticosteroids for life such as Addison's disease. Both are corticosteroids. Prednisone is about 5 times stronger than hydrocortisone. Prednisone also lasts longer in your system. 5mg of prednisone would be equal to 20mg of hydrocortisone. That dosage may need to be repeated more than once per day. I dont know your particulars but most any medical professional would know the conversion . I am going to say it must have something to do with the dosage. It could also be any number of other auto immunes. I would get checked out.

Hi there and thank you for your input. I do have Addison's Disease and have been treated with low dose prednisone since 2008. We just thought switching it up might prove beneficial perhaps ? But I have been going through a lot of issues lately and my latest ER visit was because of the swelling and possible minor congestive heart failure.. I need some more testing before that is conclusive. My new endocrinologist calculated what the conversion doses should have been (morning & afternoon) ... but things just didn't work out and as I have said since going back to the prednisone the swelling has gone down quite a bit. I have a truck load of conditions so you never know for sure which one is the culprit .. this can be exhausting and testing along with biopsies take a long time ... I could be pushing up daisies before it is resolved ? LOL

I understand. Chasing these little things that are ruining our lives can be frustrating. It took me 4 months to figure out PMR. All my Dr's thought I was nuts. Finally I figured it out. Good luck.

It does wear us down ... I feel exhausted all the time mentally and physically. My husband said at one time "you are doing "their" job for them by researching so much and coming up with answers they didn't bother to think of"
Some times I wonder why I do it myself ... probably my OCD has a hand in it.
But ? it will be getting warmer here in the Great White North and my garden is waking up ... I just want to be able to have fun with it, enjoy new plants , watch them survive me ? LOL ... I was so excited about a new Gingko tree planted in the front garden .. I was beside myself because Fall is my favorite season and Gingko leaves are so intensely, brilliant gold .. nature helps me so much. I hope everyone on here has that little happy place to go to when things are rough.

I have dermatamyositis when I first got sick my legs were massive prednisone was the only thing that helped that and the nausea I am coming up on 8 years I am still on low dose prednisone everyday and will probably be on it the rest of my life if I try to cut it really low nausea comes back

Hello there .. I had to look up your condition, it must be so painful for you. Prednisone can get a bad wrap but there are many of us out here that really find that it helps. I know I am on it for the rest of my life and have been since 2008 .. I have gained weight just this past 18 months , no answers to that I am afraid but I keep trying.
You have found your sweet spot with prednisone, so don't let any doctors tell you different ! Good luck !!

Dr Megan is pharmacist specializes in prednisone. She does articles and sells a product. Her website has many of her articles. They are free to access. You get so much more than your Dr will give you. Her videos can be lengthy and she can be boring to listen. She has one on prednisone love - hate relationship. Here is one of her articles. https://www.youtube.com/watch?v=mLMjDbOubKc