Radiation of spleen side effects…

Posted by tiger1 @tiger1, Jun 9 10:13am

I am 82 years old with B cell lymphoma….I take Brukinsa and immune therapy infusions. I am stable but spleen is large….if I get radiation will I be able to remain independent?

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Yes, you can potentially remain independent after radiation therapy for an enlarged spleen, but it depends on the cause of the splenomegaly, the specific radiation treatment, and your individual response to treatment. Radiation therapy can help shrink an enlarged spleen and alleviate symptoms, but it can also affect the spleen's function and increase the risk of infections.

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If you have your spleen radiated does this permanently keep the spleen normal size? What are the most common side effects of having your spleen radiated

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Profile picture for 12ty @12ty

If you have your spleen radiated does this permanently keep the spleen normal size? What are the most common side effects of having your spleen radiated

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Hi @12ty. While you’re waiting for other members to reply about their experience with splenic radiation therapy, I wanted to welcome you to Mayo Connect.

From my understanding, low dose radiation may be used to reduce the size of the spleen in certain medical conditions. Whether the treatment is permanent or not may depend on the underlying disease.

Were you recently diagnosed with an enlarged spleen possibly caused by a blood cancer?

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