I've been dealing with RA for 4 years now. I don't believe I've ever been in remission. I'm currently on Methotrexate and Hydrocloroquine. I'm allergic to sulfa drugs so I'm considering biologics. I'm currently trying to figure out what my treatment goals should be so I can determine if where I am is good enough. I'm currently out on std due to fatigue and brain fog. I couldn't get syringes in May for 3 weeks so it threw me into a major flare. I was then diagnosed with tricompartmental degenerative disease in both knees. Oh joy! So is the treatment goal low crp/esr levels, more good days then bad, no pain, or what?