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Diffuse large B-cell lymphoma (DLBCL): R-CHOP-14 or 21

Posted by fwpoole @fwpoole, Jul 22, 2019

With DLBCL, is there any benefit of doing R-CHOP therapy every 14 days VS 21 days, besides getting it I’ve with quicker? Information on web is spotty and inconclusive, at best yet, both cycles are approved. I’m a 64 year old male who was relatively good health before.

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Lori, Volunteer Mentor | @loribmt | Jul 23 8:12am
In reply to @kippi1950 "We are currently with Memorial Sloan Kettering and Yale. Both use bispecific antibody treatments in cases..." + (show)
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We are currently with Memorial Sloan Kettering and Yale. Both use bispecific antibody treatments in cases where R-CHOP is regarded as deleterious.
Not without side effects but you are treated as outpatient, an indication of manageable side effects. An example: an auto injection of white blood count stimulation at home.

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@kippi1950 Thank you for sharing this information about the bispecific antibody treatments that might be used instead of more intensive chemotherapy if possible. This would be a good subject for @kat7707 to discuss with her oncology team! I know she’s really reticent to begin chemotherapy so this may be a viable alternative for her.

I’m posting a link to your previous discussion about your wife’s DLBCL treatment for @kat7707 as a refresher. Mosunetuzumab plus polatuzumab vedotin (BiTE) therapy for DLBCL
https://connect.mayoclinic.org/discussion/bite-therapy-for-dlbcl/
How well is your wife tolerating the treatments? Have the followup test results been showing improvements?

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