Has anyone had the PSMA-PET scan? Was cancer found?

Hi Colleen,
Yes, my urologist scheduled the PET scan because after 4 years of PSA readings of 0.00, it has risen to 0.2. I had the scan yesterday, and hope it picked up where the cancer cells are located.

New question: Do you have data as to what percentage of patients who have their prostate removed, and have radiation treatment, later experience a recurrence of their prostate cancer?

Does anyone know where a PSMA-Pet Scan testing location might be in Arizona. We live in Prescott.

After two years of Lupron and xtandi my psa dropped to undetectable. Went off everything for three months and psa started to climb…by 6 months it went from 1 to 5.
Had the psa pet scan and found tumors in neck vertebrae. So back on Lupron and xtandi and will radiate the neck. Wouldn’t have found the new tumors without the psa pet scan. Best of luck to you.

To continue, after the cancer was found to be isolated in the pelvis, I was treated with five rounds of SBRT. Three months later my PSA was undetectable. This is after 21 years since diagnosis, surgery, then first recurrence treated with radiation, second recurrence treated with Lupron, third recurrence scanned then radiation. Rule of thumb: get scanned, then treated. If you can see cancer, you know better how to treat it. Any recurrence should be seen as an opportunity to kill it. Get second opinions and seek curative treatment, if possible. Don’t settle for palliative treatment except as last resort. Finally, if you aren’t satisfied with your local doctors, got to a center of excellence. I had better communication with docs at UCLA than I did at home.

PSMA Pet is much more accurate in detecting cancer outside the prostate than Bone or MRI. I had done extensive research before I saw oncologist or radiologist and knew I wanted PSMA. Because wait time to obtain Pet was 2+ months, went ahead with bone and MRI since those could be scheduled quickly. Radiologist indicated that bone and MRI would not have been necessary had PET been available quickly. Happy I did all! Also, had Decipher genetic test which I would highly recommend if your insurance will cover. Best to you!

I have not had the newer PSMA scans., mainly because I have not needed them. Still, should I need them, my medical team and I have decision criteria as to when to image. One of those criteria is a continuous rise in PSA that goes above .5. These scans can detect at lower PSAs but .5-1.0 is where statistically higher probability of locating sites of recurrence comes into the decision making process.

The question you want to ask is does waiting to image at a PSA of .5 or higher change the treatment decision and outcome versus imaging at a lower PSA and a decreased probability of it locating any sites of recurrence. A part of that decision is micro-metastatic disease, sites too small for the scans to identify. As an example, of the imaging locates several sites, would you decide on radiation treatment only to those sites or would you add short term systemic therapy such as ADT to deal with micro-metastatic disease?

As to your insurance company, they may very well be hiding behind old NCCN guidelines that required you to use conventional imaging first before using the PSMA ones, after all, they are cheaper and that's what insurance companies do.

I would consider appealing and cite NCCN guidelines
https://www.urotoday.com/video-lectures/nccn-prostate-cancer-guidelines-review/video/2365-nccn-guidelines-staging-evaluation-and-imaging-approaches-in-prostate-cancer-christopher-wallis-and-zachary-klaassen.amp.html
https://www.urologytimes.com/view/psma-pet-imaging-modalities-added-to-nccn-guidelines-for-prostate-cancer

The newer scans are indeed worth it. In my case, and using Gallium 68 tracer, four cancerous pelvic lymph nodes were found at PSA 1.0. These newer scans are sensitive as low as PSA .2 but the sweet spot seems to be .5 or .6.

Hi Bandit11 - I am curious as to why your physician ordered a PSMA-PET scan after previous MRI and bone scan showed no cancer present?

To Everyone Else - After having prostate removed, radiation therapy and 4 years of 0.00 PSA, I have a PSA that has risen to 0.2. This is supposed to be the lowest figure that the new PSMA-PET scan can locate, but I wonder if this newly approved scan will find it at this level. Can anyone comment on whether they had this scan at around 0.2 , and what was the result? Was the cancer located? Hector13

Had PSMA pet scan after MRI and bone scan. No cancer indicated outside prostate confirming previous tests.

Indeed, I have had the scan and it just may have helped killed my cancer for good. My PSA was rising fast. By the time I got the PSMA PET scan with gallium 68 at UCLA the PSA was 1.0. The scan showed four pelvic lymph nodes had cancer but nowhere else. I came back home to WV and got 5 SBRT radiation treatments. A month later the PSA was .5. Two months after that it was undetectable. I’m also taking Lupron and Nubeqa. All of this after being treated for this cancer for more than 20 years. I had surgery, then follow up radiation, then Lupron, and now this, three recurrences. Time will tell if the cancer is truly gone but I’m hopeful. The PSMA scan is a life changer and the folks at UCLA couldn’t have been kinder or more helpful. Best of luck.