1. < Prostate Cancer

PSA detectable 18 mos after prostatectomy

Posted by Ksusan @kscharmer, Jan 10 3:10pm

My husband had a prostatectomy in June 2022. Postsurgery PSA tests were all undetectable < .10 until January 8, 2024. The PSA result was .14
Does this mean his cancer has returned? Can PSA fluctuate?
We spoke to a friend who had a prostatectomy 9 yrs ago and had two detectable PSA >.10 tests then returned to undetectable. Is this typical?

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

billfarm | @billfarm | Jan 26 8:41pm
In reply to @mmuise1 "Hello Group: I had Robotic Prostate Surgery Aug. 2, 2022. Had 5 PSA tests since surgery...." + (show)
@mmuise1

Hello Group:

I had Robotic Prostate Surgery Aug. 2, 2022. Had 5 PSA tests since surgery. Here are the levels 0.06; 0.11; 0.12; 0.13; 0.13. Met with Radiation Oncologist last week after last PSA test and he recommended that I have another PSA test in April. He said he follows the American Guidlines that which indicates radiation from 0.18 to 0.23. Has anyone experienced rising PSA post surgery and if so, what were the next steps?

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Psa 1.8 then 2.2 post surgery. Got put on adt and psa dropped in 30 days undectable 11 months later. Drs want pelvic radiation therapy now.

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mmuise1 | @mmuise1 | Jan 29 4:05pm
In reply to @jsh327 "I recommend considering these inputs. They help to explain potential next steps, when, and why. At..." + (show)
@jsh327

I recommend considering these inputs. They help to explain potential next steps, when, and why. At your level of PSA, the challenge is knowing where to radiate.
"What to ask when PSA is rising after the initial treatment:"
PCF - https://www.pcf.org/about-prostate-cancer/diagnosis-staging-prostate-cancer/psa-rising/what-to-ask-when-your-psa-is-rising-after-initial-treatment/
"Rising PSA after initial treatment. PCRI" - https://www.youtube.com/watch?v=X_FtOBTIOj0

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Thanks you for this information and support.

Regards,
Maurice

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Moderator
Colleen Young, Connect Director | @colleenyoung | Feb 4 3:46pm
In reply to @mmuise1 "Hello Group: I had Robotic Prostate Surgery Aug. 2, 2022. Had 5 PSA tests since surgery...." + (show)
@mmuise1

Hello Group:

I had Robotic Prostate Surgery Aug. 2, 2022. Had 5 PSA tests since surgery. Here are the levels 0.06; 0.11; 0.12; 0.13; 0.13. Met with Radiation Oncologist last week after last PSA test and he recommended that I have another PSA test in April. He said he follows the American Guidlines that which indicates radiation from 0.18 to 0.23. Has anyone experienced rising PSA post surgery and if so, what were the next steps?

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You may also be interested in these discussions related to rising PSA: https://connect.mayoclinic.org/group/prostate-cancer/?search=Rising+PSA#discussion-listview

- Rising PSA years after radical prostatectomy
https://connect.mayoclinic.org/discussion/rising-psa-2years-after-radical-prostatectomy/

@mmuise1, any update? What next steps has your cancer team suggested for you?

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Moderator
Colleen Young, Connect Director | @colleenyoung | Feb 6 3:26pm
In reply to @breisch "has any one used xtandi drug for cancer" + (show)
@breisch

has any one used xtandi drug for cancer

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Hi @breisch, welcome. Several members share their experiences with enzalutamide (Xtandi) in this related discussion:

- Enzalutamide (Xtandi): Anyone have experience with this drug?
https://connect.mayoclinic.org/discussion/xtandi-2/

Click the link and join the conversation.

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dontpanic67 | @dontpanic67 | Feb 7 1:37pm
In reply to @mmuise1 "Hello Group: I had Robotic Prostate Surgery Aug. 2, 2022. Had 5 PSA tests since surgery...." + (show)
@mmuise1

Hello Group:

I had Robotic Prostate Surgery Aug. 2, 2022. Had 5 PSA tests since surgery. Here are the levels 0.06; 0.11; 0.12; 0.13; 0.13. Met with Radiation Oncologist last week after last PSA test and he recommended that I have another PSA test in April. He said he follows the American Guidlines that which indicates radiation from 0.18 to 0.23. Has anyone experienced rising PSA post surgery and if so, what were the next steps?

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Had aPSMA PeT to rule out spread or if we can find the cancer if no spread there will offer salvage radiation for cure while you’re numbers are still low good luck

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