Prostate cancer treated with Leuprolide

Posted by donnelson @donnelson, May 25, 2016

I had 43 days of prostate cancer radiation about 5-6 years ago. My PSA becgan to rise in summer of 2014. Suddenly it went from 5 to 20 in 4 months, only to drop a bit the next week. My doctor suggets Leuprolide which is administered every 6 months by a shot. I’ve read many bad side affects(swelling of feel and legs, visual changes, hot flashes and generally lower testrosterone levels). Have others had this problem? I’m wondering if I should wait a month and have the PSA drawn again?.

i had same thing; 43 days radiation , shot every 6 months, I don’t know if my shot is exactly the same but I have hot flashes and takes all the testosterone out. I have 3 month check ups and the shot is given every 6 months. my doctor gets a blood sample every 3 months and gets the psa from that. he shows me on the computer diagram screen. it gives a graph that shows if it’s going down.
yours no doubt knows the psa count. he will give it to you if you ask, I think

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@morris

i had same thing; 43 days radiation , shot every 6 months, I don’t know if my shot is exactly the same but I have hot flashes and takes all the testosterone out. I have 3 month check ups and the shot is given every 6 months. my doctor gets a blood sample every 3 months and gets the psa from that. he shows me on the computer diagram screen. it gives a graph that shows if it’s going down.
yours no doubt knows the psa count. he will give it to you if you ask, I think

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Thank you. I’ve had such bad side affects reported on this blog that I’m reluctant ;to try it. The blog yesterday from @flor was the first ray of hope. My radiation was about 5 years ago and since then the psa has been low (1-2). Last month it was 20 and a week later was 19. I guess I’ll have to bite the bullet.

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There is some question about Leuprolide ande Lupron. I’m assuming that they are the same? My urologist has agreed to another psa to see whether there has been a change. since it shot up so quickly, I’m wondering if it is a fluke. He agreed that there is a major lifestyle change that happens with this drug.. I’m wondering if there is an alternative? Also once he once told me that psas at 50 and more were not uncommon??

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Hi @donnelson. I looked it up and you are correct… they are one in the same. Leuprolide is the generic name and Lupron is one of the brand names. Glad to hear you pushed back on your doctor a little and are asking some critical questions about what’s right for you. It’s so important that we act as our own health advocates. I didn’t see much information about alternatives. Have you asked your doctor about an alternative? Let us know how your next PSA goes.

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interresting,reply.
Most definitely. I certainly,wish we had done that in my husbands case. Good luck
Success101

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@donnelson

Thank you.  You re the first to make a positive response.  The others sounded like like a death or at the least a torture treatment.

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the first thing thatnyou should know is that you and your wife are going to make very drastic options when you start lupron. My husband and I have been able to live in a different way with no sex at all, we didnt want to use the bomb. I prefer that He is alive than not having sex

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@donnelson

Thank you.  You re the first to make a positive response.  The others sounded like like a death or at the least a torture treatment.

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That is something o think about! Are there no other treatments?

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@donnelson

Thank you.  You re the first to make a positive response.  The others sounded like like a death or at the least a torture treatment.

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I dont think so but as I said before he has been alive for 15 years with this treatment . I think that another solution is doing another surgery to remove your testicles.

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@donnelson

Thank you.  You re the first to make a positive response.  The others sounded like like a death or at the least a torture treatment.

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It just gets better and better

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@donnelson

Thank you.  You re the first to make a positive response.  The others sounded like like a death or at the least a torture treatment.

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is it possible to get all the Lupron comments on one page so I could print them and show them to my doctor??

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@donnelson

There is some question about Leuprolide ande Lupron. I’m assuming that they are the same? My urologist has agreed to another psa to see whether there has been a change. since it shot up so quickly, I’m wondering if it is a fluke. He agreed that there is a major lifestyle change that happens with this drug.. I’m wondering if there is an alternative? Also once he once told me that psas at 50 and more were not uncommon??

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Don, suppression of testosterone is the standard next level of treatment for prostate cancer that has recurred after first or first and 2nd level treatments have failed. By first and second I mean surgery and/or radiation. If you still have PSA after the prostate area has been aggressively treated the assumption is that enough cells have accumulated somewhere outside the prostate capsule to be able to create PSA, in other words, a tumor, however small. Since they don’t know exactly where it is, they treat you systemically by depriving the prostate cancer cells of their primary growth driver, testosterone. Some men have minimal side effects, some serious. Its very subjective. Your doctor should have explained this to you as well as the fact that their are no clear alternative treatments available now but some are emerging. Try to exercise as much as you can within reason. Ask for help with any depression if it is a problem. Here is one website that covers many topics related to advanced prostate cancer: http://malecare.org/advanced-prostate-cancer/
Here is another and there are more: http://www.yananow.org/Experiences.shtml
By all means get your PSA tracked as often as advised and avoid any temptation to self-treat based on unproven anecdotal evidence.
I’ve been treated twice, surgery and radiation, and it looks like I’m on my second recurrence. I’ve had low testosterone without getting Lupron and I know how it feels, in my case awful. But, considering the alternative, its worth working with it. Let me know how you’re doing.

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@donnelson

There is some question about Leuprolide ande Lupron. I’m assuming that they are the same? My urologist has agreed to another psa to see whether there has been a change. since it shot up so quickly, I’m wondering if it is a fluke. He agreed that there is a major lifestyle change that happens with this drug.. I’m wondering if there is an alternative? Also once he once told me that psas at 50 and more were not uncommon??

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I had an appointment with a medical oncologist this morning and we went over all the options. My psa at the last test was 30 which means that is it still rising, although some psa’s have actually gone to 10,000. I m going to have a bone scan and a CTScan, last ones were a few months ago next week. Then I will meet with her and see what she suggests based on the results. I could start with 1 Lupron shot and see how that works. Then meet with the urologist and perhaps go on a regular schedule with frequent psa tests, etc.She said the worst side affect for most men is hot and cold flashes.(at last we get to experience first hand what women go through). Some are very strong and others had minor problems. There are pills for that, she said. Since I also have afib I am used to frequent tests to gage the affects of various medication levels. Since I was seriously dizzy with gabapentin that is a real possibility here, she said.

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