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Prostate cancer treated with Leuprolide

Prostate Cancer | Last Active: Dec 1, 2022 | Replies (82)

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@donnelson

There is some question about Leuprolide ande Lupron. I'm assuming that they are the same? My urologist has agreed to another psa to see whether there has been a change. since it shot up so quickly, I'm wondering if it is a fluke. He agreed that there is a major lifestyle change that happens with this drug.. I'm wondering if there is an alternative? Also once he once told me that psas at 50 and more were not uncommon??

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Replies to "There is some question about Leuprolide ande Lupron. I'm assuming that they are the same? My..."

Don, suppression of testosterone is the standard next level of treatment for prostate cancer that has recurred after first or first and 2nd level treatments have failed. By first and second I mean surgery and/or radiation. If you still have PSA after the prostate area has been aggressively treated the assumption is that enough cells have accumulated somewhere outside the prostate capsule to be able to create PSA, in other words, a tumor, however small. Since they don't know exactly where it is, they treat you systemically by depriving the prostate cancer cells of their primary growth driver, testosterone. Some men have minimal side effects, some serious. Its very subjective. Your doctor should have explained this to you as well as the fact that their are no clear alternative treatments available now but some are emerging. Try to exercise as much as you can within reason. Ask for help with any depression if it is a problem. Here is one website that covers many topics related to advanced prostate cancer: http://malecare.org/advanced-prostate-cancer/
Here is another and there are more: http://www.yananow.org/Experiences.shtml
By all means get your PSA tracked as often as advised and avoid any temptation to self-treat based on unproven anecdotal evidence.
I've been treated twice, surgery and radiation, and it looks like I'm on my second recurrence. I've had low testosterone without getting Lupron and I know how it feels, in my case awful. But, considering the alternative, its worth working with it. Let me know how you're doing.

I had an appointment with a medical oncologist this morning and we went over all the options. My psa at the last test was 30 which means that is it still rising, although some psa's have actually gone to 10,000. I m going to have a bone scan and a CTScan, last ones were a few months ago next week. Then I will meet with her and see what she suggests based on the results. I could start with 1 Lupron shot and see how that works. Then meet with the urologist and perhaps go on a regular schedule with frequent psa tests, etc.She said the worst side affect for most men is hot and cold flashes.(at last we get to experience first hand what women go through). Some are very strong and others had minor problems. There are pills for that, she said. Since I also have afib I am used to frequent tests to gage the affects of various medication levels. Since I was seriously dizzy with gabapentin that is a real possibility here, she said.

There is the idea of 'Watchful Waiting' but it sounds like with a rising PSA treatment is advisable. But at the end of the day its your call after you get the info. I encourage you to check some of those support groups. Keep us in the loop.

HAVE YOU HAD A PROSTATECTOMY, FROM MY HUSBANDS EXPERIENCE THAT HE HAD A VERY AGRESSIVE PROSTATE CANCER MY SUGGESTION GO WITH LUPRON AND SEE IF YOUR PSA LOWERS. MY HUSBANDS IS 0.07. THIS MEANS UNDETECTEBLE. WISH YOU ALL THE LUCK . FLOR