Prolia dangers for those with autoimmune disease

The impact of Prolia has horribly worsened my precarious autoimmune conditions. So much so that Amgen legal dept contacted me within weeks of my injection.

In the fine print of clinical info for physicians, after all other adverse reactions are listed, Amgen states that Prolia can cause immunogenicity.

My reaction started within seconds of the injection. It affected my brain immediately. Subsequently a wave of encephalitis flares hit. This has been topped by flares of all AI conditions & has been relentless.

Now my jaw & teeth are involved. I have new skeletal pain.

In desperation I called Amgen immediately for antidotes like dialysis. There isn’t anything that can be done.

Literature states that severe AI flares can start immediately or months later. It’s also stated these flares might continue after the initial dose wears off.

Of all the Rx I’ve been administered to treat serious rare & “mainstream” autoimmune diseases, Prolia is what’s taking me down now, after my ongoing push to get through since 2011.

I don’t know what the future holds but the present has no offerings for medical stability.

As always, pharmaceutical companies can afford damages or even losses of patients then move on without looking back.

I’ve reported to FDA. I don’t understand how a potent drug with so many open ends & no solutions would be allowed on the market. This is the egregious process of the drug industry.

I get that Prolia has helped people. But it’s still unknown how long term use will impact these patients.

And my final question is why an immune suppressing, immune modulating drug would be given to a healthy person? As one who needs immune suppression to reach stability (sometimes), I know the fallout all too well. It can open up a whole new can of worms.