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Prolia dangers for those with autoimmune disease
The impact of Prolia has horribly worsened my precarious autoimmune conditions. So much so that Amgen legal dept contacted me within weeks of my injection.
In the fine print of clinical info for physicians, after all other adverse reactions are listed, Amgen states that Prolia can cause immunogenicity.
My reaction started within seconds of the injection. It affected my brain immediately. Subsequently a wave of encephalitis flares hit. This has been topped by flares of all AI conditions & has been relentless.
Now my jaw & teeth are involved. I have new skeletal pain.
In desperation I called Amgen immediately for antidotes like dialysis. There isn’t anything that can be done.
Literature states that severe AI flares can start immediately or months later. It’s also stated these flares might continue after the initial dose wears off.
Of all the Rx I’ve been administered to treat serious rare & “mainstream” autoimmune diseases, Prolia is what’s taking me down now, after my ongoing push to get through since 2011.
I don’t know what the future holds but the present has no offerings for medical stability.
As always, pharmaceutical companies can afford damages or even losses of patients then move on without looking back.
I’ve reported to FDA. I don’t understand how a potent drug with so many open ends & no solutions would be allowed on the market. This is the egregious process of the drug industry.
I get that Prolia has helped people. But it’s still unknown how long term use will impact these patients.
And my final question is why an immune suppressing, immune modulating drug would be given to a healthy person? As one who needs immune suppression to reach stability (sometimes), I know the fallout all too well. It can open up a whole new can of worms.
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@missey hi ~ Prolia isn’t a statin, it’s a biological for bone density.
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2 ReactionsHello,
I am reading this thread with great interest. I was diagnosed with osteoporosis, which improved with supplements and diet two years ago, changed to osteopenia. I’ve had 2 lumbar fusions, and last year 2 cervical fusions due to hardware failure.
After being diagnosed with PMR in January, I was put on steroids, 8 mg daily. In April, after a day out enjoying my grandchildren play soccer for a few hours, I started feeling ill. I should have gone to the ER, but relied on my NS to order testing to see what was wrong.
Within a few weeks a CT scan revealed I had suffered a bilateral insufficiency fracture in my sacrum ala, which I’ve read is mainly caused by corticosteroid use and osteoporosis in the elderly. My Rheumatologist just gave me an injection of Prolia last month. I have to say I have resisted any osteoporosis drugs for years, mainly because of the side effects.
So far, I have not noticed any side effects and I pray I don’t.
Trying to navigate side effects and risk versus benefit as an autoimmune patient is pretty daunting. I hope and pray the best for all of us!
For a minute I thought I was reading something I wrote in. I am in such trouble since last May with my 21st Prolia shot that they tell me was not in the “soft recall” that I found out about many months later. And then at six months Jubbonti was given without any discussion and I have many of the extreme side affects and pain that 24 told me they dont know what else to do!!!
I was told Jubbonti was bio similar to PROLIA. After my injection of Jubbonti, I had multiple adverse side effects., and still do. I will never allow Jubbonti to be injected into me again, EVER!
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1 ReactionI am suffering from the severe adverse effects from Jubbonti. So I called my drs and they tried and sent me for many diagnostic tests and left scratching their heads. Now what?!
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