Premarin vaginal cream vs Estradiol vaginal cream

I am using estrogen cream twice a week as well and it is starting cause a lot of irritation .Does anyone have suggestions on what to use to help with burning and irritation ? I have been using Zinc ointment, it helps a bit but there might be another answer? Thanks

I have tried both ,i don't find any difference however on premarin is less expensive in canada 🇨🇦. It might be a bit stronger in odor . That would be interesting to find out if there is a difference in the products .

I use the generic estradiol cream and have discovered the manufacturer makes a difference in how I react. I happen to get a cream from a different company since that is what the pharmacy had at the time. I had burning. My gyn now writes the RX for the
generic brand that does not cause irritation.