Post viral syndrome peripheral nerve hyperexcitability
Hi everyone,
I’m a 36-year-old navigating recovery from what’s been described as post-viral small fiber involvement and motor nerve hyperexcitability.
How It Began:
It started after a viral illness in August 2024, during a time when my whole family had upper respiratory symptoms.
I developed fever, diffuse headache, and left-sided temple pain, which later localized and became persistent.
By January 2025, I began to experience:
Burning sensations
Pins and needles
Odd wet or sunburn-like skin feelings
Muscle fasciculations (twitches) across my body
Migratory muscle pain and intermittent joint discomfort
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Workup So Far:
MRI of brain and cervical spine: Normal
Autoimmune workup: Negative
Skin biopsy: Normal epidermal nerve fiber density
Nerve conduction studies & EMG (lower extremities): Normal
CBC, CMP, CRP, ESR, CK, aldolase, B12: All normal
No evidence of large fiber neuropathy or motor neuron disease
No clinical weakness or atrophy
---
Current Working Diagnosis:
Post-viral small fiber sensitization
Motor nerve hyperexcitability (likely benign fasciculation syndrome or similar)
Significant health anxiety, especially due to my medical background and profession
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What’s Helping Me:
Gabapentin (600 mg at night)
Supplements:
Magnesium glycinate
CoQ10
Alpha-lipoic acid (ALA)
Omega-3
Curcumin
B-complex
Vitamin D3 + K2
Ashwagandha, glycine, apigenin (for calming and sleep)
Exercise: Strength remains intact and working out reinforces my confidence
Mind-body tools:
Headspace and Curable app
Weekly visits with a psychologist
Gratitude journaling
Somatic calming techniques (breathing, grounding, mantra work)
New mantra I use daily:
> “One in a million. I am strong. This will pass.”
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Biggest Lessons:
Even with scary symptoms like widespread twitching or burning, the body can be in a state of hyperawareness, not disease.
I’ve learned the importance of regulating fear and stress to support nervous system healing.
Benign doesn’t mean painless—but it does mean hopeful.
Working with a neurologist, psychologist, and staying grounded in scientific reasoning has helped me reclaim my peace.
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Happy to connect with anyone navigating something similar. You're not alone—and your body is capable of calming, rewiring, and healing.
Interested in more discussions like this? Go to the Neuropathy Support Group.
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I also have increasing swelling edema around my ankles behind my ankles in front of my ankles and all on my shit for no real reason, but I have had burning and redness and tingling for a long time only getting worse spread to my other foot. No doctor can give me the answer for my edema except to say I I don’t move enough, but I move as much as I can and I still walk relatively a lot so I’m wondering if anyone has something like that as well. The swelling that causes a lot of discomfort
@SusanEllen66
Hi Susan I feel like what I am expericing does have some overlap with FND. Thank you for the suggestion.
Hello @dlydailyhope
I just stumbled over your post from April last year.
I have been struggling with neuropathy for years. Influenza last January caused major increase of symptoms.
I have tested blood for Epstein Barr, result showed extreme high antibodies over 700 which suggests I have recurring viral reactivation.
Any ideas how to prevent viruses from reactivating and keeping them dormant, as you have suggested?
Any input/experience appreciated 🙂
Thank you for posting this. I have a lot of the same symptoms with similar tests and thrown under the fibromyalgia group. All the best.
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