Post viral syndrome peripheral nerve hyperexcitability

Posted by josh701 @josh701, Apr 6 9:51am

Hi everyone,
I’m a 36-year-old navigating recovery from what’s been described as post-viral small fiber involvement and motor nerve hyperexcitability.

How It Began:

It started after a viral illness in August 2024, during a time when my whole family had upper respiratory symptoms.

I developed fever, diffuse headache, and left-sided temple pain, which later localized and became persistent.

By January 2025, I began to experience:

Burning sensations

Pins and needles

Odd wet or sunburn-like skin feelings

Muscle fasciculations (twitches) across my body

Migratory muscle pain and intermittent joint discomfort

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Workup So Far:

MRI of brain and cervical spine: Normal

Autoimmune workup: Negative

Skin biopsy: Normal epidermal nerve fiber density

Nerve conduction studies & EMG (lower extremities): Normal

CBC, CMP, CRP, ESR, CK, aldolase, B12: All normal

No evidence of large fiber neuropathy or motor neuron disease

No clinical weakness or atrophy

---

Current Working Diagnosis:

Post-viral small fiber sensitization

Motor nerve hyperexcitability (likely benign fasciculation syndrome or similar)

Significant health anxiety, especially due to my medical background and profession

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What’s Helping Me:

Gabapentin (600 mg at night)

Supplements:

Magnesium glycinate

CoQ10

Alpha-lipoic acid (ALA)

Omega-3

Curcumin

B-complex

Vitamin D3 + K2

Ashwagandha, glycine, apigenin (for calming and sleep)

Exercise: Strength remains intact and working out reinforces my confidence

Mind-body tools:

Headspace and Curable app

Weekly visits with a psychologist

Gratitude journaling

Somatic calming techniques (breathing, grounding, mantra work)

New mantra I use daily:

> “One in a million. I am strong. This will pass.”

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Biggest Lessons:

Even with scary symptoms like widespread twitching or burning, the body can be in a state of hyperawareness, not disease.

I’ve learned the importance of regulating fear and stress to support nervous system healing.

Benign doesn’t mean painless—but it does mean hopeful.

Working with a neurologist, psychologist, and staying grounded in scientific reasoning has helped me reclaim my peace.

---

Happy to connect with anyone navigating something similar. You're not alone—and your body is capable of calming, rewiring, and healing.

Interested in more discussions like this? Go to the Neuropathy Support Group.

Profile picture for daj3333 @daj3333

Do you mind telling us what ballpark timeframe you were given for recovery?

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No concrete time table. He said months to years... I'm mentally preparing for this is just my new norm. As long as things don't progress I am happy I am complete function and can sleep at night with the help of medication.

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Hi Josh,

I know this is a bit of an old post but I found it today and it feels like I could have written it myself. I am having so many unusual sensations after an unknown illness and I keep being told it’s likely just anxiety. It’s getting better and better slowly, though. How are you doing? Any improvements?

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O am going through similar things and really struggling

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I have had exactly the same even symptoms, even down to what your blood work was and supplements, although I take a couple more, I am a nutritionist. I’ve been to the neuro worst day of my life, same tests as you and spiralled into anxiety and despair. Very hard to climb out of the hole when you get there. I had significant stress before I started noticing the twitching with a bout of Covid preceding it. The whole thing has been hideous but trying to keep moving forward !!

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Profile picture for monzad17 @monzad17

I have had exactly the same even symptoms, even down to what your blood work was and supplements, although I take a couple more, I am a nutritionist. I’ve been to the neuro worst day of my life, same tests as you and spiralled into anxiety and despair. Very hard to climb out of the hole when you get there. I had significant stress before I started noticing the twitching with a bout of Covid preceding it. The whole thing has been hideous but trying to keep moving forward !!

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Just saw your post. I posted upthread in April about my progress. I’m happy to say I’ve continued to improve in most ways, though still have some issues. Overall, I’m ecstatic to be doing so well. Glad to see you moving forward. I certainly hope you and others have improvement too.

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Profile picture for celia16 @celia16

Just saw your post. I posted upthread in April about my progress. I’m happy to say I’ve continued to improve in most ways, though still have some issues. Overall, I’m ecstatic to be doing so well. Glad to see you moving forward. I certainly hope you and others have improvement too.

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Thank you so much that gives me hope .. some symptoms have improved although I’m not sure how much was also masked by chronic stress.

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Profile picture for gabi04 @gabi04

Hi Josh,

I know this is a bit of an old post but I found it today and it feels like I could have written it myself. I am having so many unusual sensations after an unknown illness and I keep being told it’s likely just anxiety. It’s getting better and better slowly, though. How are you doing? Any improvements?

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Hi Gabi about the same. Still bodywide twitches, for the past 2 months I have had this stiffness in my right glute and calf. Not sure what to think of it seems to be pretty common the BFS reddit. I just hit my 6 months mark of fasciculations without any significant weakness so I take that as a win. God bless

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