Possible failure of Nissen Fundoplication (2021)

Posted by ufoundme @ufoundme, Dec 28, 2025

I had a Nissen Fundoplication in July 2021 due to hiatal hernia, severe gerd, etc. I had major complications in September 2021 prompting the the surgeon to redo the surgery but adding an "anchor" from the stomach to my abdomen. I've had mild gerd but it has been manageable by meds for 4 years. Recently I got really sick (nausea & vomiting) and since then have had intractible nausea accompanied by frequent deep burping. I'm having an endoscopy next week but am very concerned the Fundoplication has failed again. Has anyone experienced something similar and what was the outcome?
53/F.

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Hi, @ufoundme. I am glad to see you create this discussion on your quest to figure out if your most recent Fundoplication is helping. I am just seeing this and first want to apologize for not commenting earlier.

I went to the home page, searched for ‘failed fundoplication’ and found quite a few comments. Most are not super recent so I kept looking until I found a newer one. @nirolk created a discussion trying to troubleshoot problems they were having following the procedure. I hope they provide an update and tag others that may have valuable input. Several discuss symptoms like yours and even failed Fundoplication. You may find it valuable to review this and other discussions as you continue to wait for others to comment.
- Post-Nissen Fundoplication Bowel, Etc., Problems: What helps? https://connect.mayoclinic.org/discussion/post-nissen-wrap-symptoms/
- Connect search in Digestive Health Support Group for Nissen Fundiplication: https://connect.mayoclinic.org/group/digestive-gastrointestinal-problems/

You mentioned having an endoscopy scheduled for earlier this month. What did you learn? How are you feeling?

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Hi Janell, thanks for checking. Since you asked, my endoscopy was normal. I won't go into any more details here but suffice it to say I can no longer take GLP-1 for weight loss..

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