MDS: Can someone explain how or why platelets go up or down quickly?

Posted by hlmcneely @hlmcneely, Sep 25, 2022

Can someone explain how or why platelets go up or down quickly. My diagnosis was MDS after a bone marrow biopsy and I was sent to a second specialist. Previous diagnosis was ITP. My question is how can platelets rise or drop within days. When I was sent for biopsy they were 64. Four days later 84. This past Tuesday 76 Friday 84. Thank you.

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suetex | @suetex | Apr 20 10:37am

I too, have MDS. My platelets go up and down too, but as yet they haven't gone so low as to cause a problem. Mostly I have low white and red cells and have recieved shots for both over time. This last go around I did feel the anemia and was weak for a few days. Haven't had to have any transfusions. The only thing that is high is my monocytes. 35% the last count. And they look normal. I am going to ask my oncologist if they are a problem, when I see him next. No professional has said anything about them. Still, I wonder....
I think my risk factor was the radiation I had for my breast cancer and a lip growth.

alpinegirl | @alpinegirl | Apr 20 11:21am

In reply to @kathy115 "My husband also has mDS. He was considered mild but his levels are very low(platelets 24)..." + (show)

I came across an article that stated MDS can come from having stomach or intestinal surgery.
I had a growth removed from my colon approximately 1-1/2 to 2 years ago. The day before
surgery my hemoglobin was 13 and seven days later was 11.7 Finally went to the doctor after
finding myself breathles at times - a CBC showed my hemoglobin was down to 6. that was the
start of my blood transfusions and my diagonosis of MDS