Pernicious Anemia and B12 Ranges

Posted by bumble81 @bumble81, Sep 18, 2019

I was diagnosed in 2015. Do any of you with PA still have symptoms related to your PA even when your B12 levels are in normal ranges? I was under the impression that getting B12 shots would eliminate any issues caused by PA.

@loisnovell Welcome to Mayo Clinic Connect, a place to give and get support.

You are wondering if your "CBC and hemoglobin all show normal readings can someone still have pernicious anemia?"

You will notice that I moved your question to a previous discussion related to this topic. I did this so you could connect with members like @peach414144 @becsbuddy . They may be able to give you information, suggestions, and/or support.

Below I have linked two other discussions related to pernicious anemia.
– Pernicious Anemia and B12 Ranges https://connect.mayoclinic.org/discussion/pernicious-anemia-2/
– Diagnosed with pernicious anemia; my stomach distends after eating https://connect.mayoclinic.org/discussion/when-i-was-diagnosed-with-pernicious-anemia-i-noticed-that-my-stomach/

You might wish to scroll through the 3 discussions and read the posts.

You said that you were showing symptoms. May I ask what kind of symptoms you are experiencing?

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@loisnovell

pernicious anemia

I have a question. If a CBC and hemoglobin all show normal readings can someone still have pernicious anemia? My Dad was diagnosed with it in his 50’s and received monthly B12 injections. I am showing symptoms of it but just had a CBC done and everything was normal.

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Hello @loisnovell, I would like to add my welcome to you. I appreciate your post about pernicious anemia. I have copied a link from Mayo Clinic's website about the way this type of anemia is diagnosed and what symptoms describe this disorder. Just click on the link, https://www.mayoclinic.org/diseases-conditions/vitamin-deficiency-anemia/diagnosis-treatment/drc-20355031,

You mentioned that your dad had pernicious anemia. Are your symptoms similar to his?

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@erikas

@loisnovell Welcome to Mayo Clinic Connect, a place to give and get support.

You are wondering if your "CBC and hemoglobin all show normal readings can someone still have pernicious anemia?"

You will notice that I moved your question to a previous discussion related to this topic. I did this so you could connect with members like @peach414144 @becsbuddy . They may be able to give you information, suggestions, and/or support.

Below I have linked two other discussions related to pernicious anemia.
– Pernicious Anemia and B12 Ranges https://connect.mayoclinic.org/discussion/pernicious-anemia-2/
– Diagnosed with pernicious anemia; my stomach distends after eating https://connect.mayoclinic.org/discussion/when-i-was-diagnosed-with-pernicious-anemia-i-noticed-that-my-stomach/

You might wish to scroll through the 3 discussions and read the posts.

You said that you were showing symptoms. May I ask what kind of symptoms you are experiencing?

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Shingles last January which lasted 7 weeks. Then Silent Reflux in March. Due to covid doctor told me to take prevacid which i did for 4 months. Now every 2 months or less an episode of distention 1-3 hours after dinner with very severe stomach pain which lasts until I take Pepto Bismol and then it so far has immediately stopped the pain. Last time i vomited. Have insomnia, on occasion restless legs, tongue feels burned at times, canker sores, occasional heart palpitations, episode of breathlessness a couple of weeks ago. Father had pernicious anemia and got monthly injections. Mother had Crohn's. Thank you for signing me up an getting me information.

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Hello @loisnovell,

You have had numerous health issues. I can understand your wanting to find some answers

What type of specialists have you seen? With the wide variety of health problems, have you considered seeking a second opinion at a multi-disciplinary health facility like Mayo Clinic or a university medical school? These types of facilities have ongoing research and are better than average at diagnosing and treating hard-to-treat problems.

Have you considered a second opinion at a health facility like these?

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@loisnovell

Shingles last January which lasted 7 weeks. Then Silent Reflux in March. Due to covid doctor told me to take prevacid which i did for 4 months. Now every 2 months or less an episode of distention 1-3 hours after dinner with very severe stomach pain which lasts until I take Pepto Bismol and then it so far has immediately stopped the pain. Last time i vomited. Have insomnia, on occasion restless legs, tongue feels burned at times, canker sores, occasional heart palpitations, episode of breathlessness a couple of weeks ago. Father had pernicious anemia and got monthly injections. Mother had Crohn's. Thank you for signing me up an getting me information.

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@loisnovell Hello. @erikas suggested that I be in touch with you about pernicious anemia. I really don’t know about pernicious anemia, but I did learn what to do when you have multiple different symptoms and nothing seems to make sense. Like @hopeful33250 suggests, going to a university medical center or some place like Mayo Clinic can make all the difference. My autoimmune disease is so new that no one here knew anything about it, so we went to the university hospital. They had a doctor who specialized in neuro-immunology!
Are you anywhere near a large hospital or university?

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@becsbuddy

@loisnovell Hello. @erikas suggested that I be in touch with you about pernicious anemia. I really don’t know about pernicious anemia, but I did learn what to do when you have multiple different symptoms and nothing seems to make sense. Like @hopeful33250 suggests, going to a university medical center or some place like Mayo Clinic can make all the difference. My autoimmune disease is so new that no one here knew anything about it, so we went to the university hospital. They had a doctor who specialized in neuro-immunology!
Are you anywhere near a large hospital or university?

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Thank you for your response. I am not unfortunately near a large hospital or university. I have made the trip from out of state to the Mayo clinic in Rochester before for surgery. It's a wonderful place. I do have an appointment now for a local physical although I couldn't get in for a few months but hopefully that will give me some answers. Thank you for your information.

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@hopeful33250

Hello @loisnovell,

You have had numerous health issues. I can understand your wanting to find some answers

What type of specialists have you seen? With the wide variety of health problems, have you considered seeking a second opinion at a multi-disciplinary health facility like Mayo Clinic or a university medical school? These types of facilities have ongoing research and are better than average at diagnosing and treating hard-to-treat problems.

Have you considered a second opinion at a health facility like these?

Jump to this post

I have traveled from out of state to the Mayo clinic in the past for surgery. It's a wonderful place. Unfortunately with the travel involved and the covid that isn't an option for me at this time. I doo now have an appointment for a local physical and hopefully that will give me some answers. Thank you so much for your information especially the article on pernicious anemia.

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@loisnovell

I have traveled from out of state to the Mayo clinic in the past for surgery. It's a wonderful place. Unfortunately with the travel involved and the covid that isn't an option for me at this time. I doo now have an appointment for a local physical and hopefully that will give me some answers. Thank you so much for your information especially the article on pernicious anemia.

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@loisnovell

I'm glad to hear that you have an appointment coming up for a physical. I hope you do get some answers.
If you read the article that I posted, did you learn anything new or anything that seemed to apply to your current health situation?

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@hopeful33250

@loisnovell

I'm glad to hear that you have an appointment coming up for a physical. I hope you do get some answers.
If you read the article that I posted, did you learn anything new or anything that seemed to apply to your current health situation?

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Yes I found it very informative and very glad that you sent it. Thank you again..

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Hello, my first auto immune disease was Hashimoto’s. Actually it was asthma and allergies as a baby. I now have gastritis, Gerd, type one diabetes, lichen planus, vitiligo, psoriasis and pernicious anemia. I am feeling like the poster child for auto immune diseases. I’m in my mid-50s. I would really like to know what the optimum levels of B12 should be for someone with pernicious anemia? I take B12 shots randomly but would really like to know how to manage this effectively. I have talk to my GP about it but it doesn’t seem like she’s very knowledgeable is there another specialist I could see?

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@roefote64

Hello, my first auto immune disease was Hashimoto’s. Actually it was asthma and allergies as a baby. I now have gastritis, Gerd, type one diabetes, lichen planus, vitiligo, psoriasis and pernicious anemia. I am feeling like the poster child for auto immune diseases. I’m in my mid-50s. I would really like to know what the optimum levels of B12 should be for someone with pernicious anemia? I take B12 shots randomly but would really like to know how to manage this effectively. I have talk to my GP about it but it doesn’t seem like she’s very knowledgeable is there another specialist I could see?

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Hello @roefote64 – Welcome to Mayo Clinic Connect. According to the National Heart, Lung and Blood Institute along with your primary care doctor the following specialists may be involved – a neurologist (nervous system specialist), a cardiologist (heart specialist), a hematologist (blood disease specialist), and a gastroenterologist (digestive tract specialist).

– NIH – Pernicious Anemia: https://www.nhlbi.nih.gov/health-topics/pernicious-anemia

Have you asked your GP if she can give you a referral to a specialist?

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