1. < Neuropathy

PEA for pain relief?

Posted by stellarg @stellarg, Nov 11 6:15pm

I tried the first 300 mg dose last evening but was awakened about 6 hrs. later with severe itching on both lower legs and ankle areas...I don't know if cause/effect applies. Has anyone else experienced similar PEA side effect?

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stellarg | @stellarg | Nov 12 9:13am

PEA (palmitoylethanolamide) is an oral supplement someone else had mentioned as working 60-70% at relieving
his neuropathy pain. Of course I couldn't find his comment after using it. There are a few vendors on Amazon which is where I bought it after reading of it here.

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2 replies
stellarg | @stellarg | Nov 12 9:15am
In reply to @stellarg "PEA (palmitoylethanolamide) is an oral supplement someone else had mentioned as working 60-70% at relieving his..." + (show)
@stellarg

PEA (palmitoylethanolamide) is an oral supplement someone else had mentioned as working 60-70% at relieving
his neuropathy pain. Of course I couldn't find his comment after using it. There are a few vendors on Amazon which is where I bought it after reading of it here.

Jump to this post

I used 1 300mg cap and had the severe itch in both lower legs and ankles. Thanks for your inquiry.
Tom B.

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ohiodoug | @ohiodoug | Nov 13 7:04am

I've been taking 1100 mg PEA for last six months in combo with another vitamin regiment (The Protocol).
Overall, my pain is better.

I get my PEA from https://thewelltheory.com/

There is research supporting PEA treating neuropathy so its worth trying! For example...

Palmitoylethanolamide in the Treatment of Chronic Pain: https://pmc.ncbi.nlm.nih.gov/articles/PMC10053226/

Effect of PEA-OXA on neuropathic pain
https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-018-1303-5
Good luck!
Doug

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1 reply
stellarg | @stellarg | Nov 13 10:24am
In reply to @ohiodoug "I've been taking 1100 mg PEA for last six months in combo with another vitamin regiment..." + (show)
@ohiodoug

I've been taking 1100 mg PEA for last six months in combo with another vitamin regiment (The Protocol).
Overall, my pain is better.

I get my PEA from https://thewelltheory.com/

There is research supporting PEA treating neuropathy so its worth trying! For example...

Palmitoylethanolamide in the Treatment of Chronic Pain: https://pmc.ncbi.nlm.nih.gov/articles/PMC10053226/

Effect of PEA-OXA on neuropathic pain
https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-018-1303-5
Good luck!
Doug

Jump to this post

Thanks for the references ohiodoug. I'm still leary of using PEA after my severe itching episode from one XGold Health 300mg . May try another brand after a short break.
The Indians (Guardians) will get 'em next year. Go tribe!

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jchet | @jchet | Nov 13 4:59pm
In reply to @stellarg "PEA (palmitoylethanolamide) is an oral supplement someone else had mentioned as working 60-70% at relieving his..." + (show)
@stellarg

PEA (palmitoylethanolamide) is an oral supplement someone else had mentioned as working 60-70% at relieving
his neuropathy pain. Of course I couldn't find his comment after using it. There are a few vendors on Amazon which is where I bought it after reading of it here.

Jump to this post

Be Careful. I ordered PEA from Amazon, but will return it as I found out that you should not take it if you’re on Eliquis (blood thinner).

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1 reply
stellarg | @stellarg | Nov 13 6:10pm
In reply to @jchet "Be Careful. I ordered PEA from Amazon, but will return it as I found out that..." + (show)
@jchet

Be Careful. I ordered PEA from Amazon, but will return it as I found out that you should not take it if you’re on Eliquis (blood thinner).

Jump to this post

Thanks for the input, jchet. I do take coumadin the old school blood thinner and have not checked with my cardiologist yet. Sometimes I DO get the correct, safe sequence for meds, which makes old age so much more fun.

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Moderator
Colleen Young, Connect Director | @colleenyoung | Nov 29 4:56pm

@stellarg and others, you may also be interested in this related discussion:
- Palmitoylethanolamide (PEA) supplement: Success with Pain & Sleep? https://connect.mayoclinic.org/discussion/pea-supplement/

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