Pancreatic Cancer Group: Introduce yourself and connect with others

Yes! I am on it now. And I am in a thread with many others on it in various cohorts. I have been on it since July 8 doing the combo RM 9805 and RM 6236. Great results. It has demolished a lung tumor and 40% shrinkage in liver tumor. Others are having similar results. I can tell you where the sites are if you would like to DM me.
Even if it clears my tumor I am going to ask for compassionate use. It is systemic but works differently than chemo.

Lastly, I have also done Gem/abraxane. For me the side effects were much easier than folfurinox. But we are all different….

Yes! I am on it now. And I am in a thread with many others on it in various cohorts. I have been on it since July 8 doing the combo RM 9805 and RM 6236. Great results. It has demolished a lung tumor and 40% shrinkage in liver tumor. Others are having similar results. I can tell you where the sites are if you would like to DM me.
Even if it clears my tumor I am going to ask for compassionate use. It is systemic but works differently than chemo.

Lastly, I have also done Gem/abraxane. For me the side effects were much easier than folfurinox. But we are all different….

Has anyone had experience with the RMC-6236 clinical trials targeting the KRAS mutations? Mine is KRAS G12V.

One of the treatment methods for liver tumors is Microwave - Radiofrequency ablation (RFA), known as “Burning”, that is, the method of destroying the tumor by burning. Today, RFA is a method that we commonly use in diseases such as colon cancer, liver metastasis and HCC. The priority in liver cancer is surgical treatment,
My doctor suggested it, we're in the same situation. I live in Turkey

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Hi, I was diagnosed with stage 2 pancreatic cancer in December 2023. Had clinical trial immunotherapy in January, and modified Whipple surgery in February 2024. 26 lymph nodes were removed, cancer was in 3 of them and in some nerve tissue - however, all my margins were clear. I began 12 rounds of Folfirinox on April 6th, just finished on September 13th. CA19-9 before Whipple was 162, after Whipple went down to 5,8,11. CT scans showed no recurrence or metastases - until my October 2nd CT scan which showed 2 lesions on my liver, 1.5 cm and .5 cm. I am interested to know whether anyone has had surgical or other treatments for pancreatic cancer metastases to the liver, and any outcomes? Thank you.

Here's my experience with Folfirinox. I was diagnosed with stage 4 pancreatic acinar cell carcinoma in Sept. of 23. I started 12 cycles of Folfirinox that ended in early April of this year. I was 74 when I started the chemo. I tolerated it well but still have some aggravating peripheral neuropathy. It's a 3 day chemo session actually. 1st day is the infusion in the cancer center. Then I went home with the pump for 46 hrs. After the pump was off, I forced myself to go to the YMCA and continue my daily long swimming exercise. I'm convinced that helped me more than anything to withstand the chemo. You_have_to try to keep your body strong. When I started the chemo, the last CT scan showed a 7.3 cm X 3.5 cm tumor on my pancreas, several cancerous lesions on my omentum (abdominal wall, I think) and 3 cancerous lesions on my liver. Biopsy confirmed all findings as cancer. At the end of chemo in April, the CT scan showed no evidence of any tumors except one remaining on my liver. My oncologist wants to have another laparoscopic exploratory procedure to check for cancer in my peritoneum and if none is present, proceed with radiation, microwaves or radioactive beads to try and get rid of the tumor on my liver. My understanding is that cancerous nodules/lesions, whatever are extremely hard to detect in the peritoneum with a CT scan. Chemo can be tough. I wish you well, ma'am. Keep your body strong.

I spoke with my oncologist today after receiving the news that my cancer had spread to my liver despite my 12 rounds of Folfirinox. Turns out it has also spread to the soft tissue in my belly. So surgery is not an option. They are starting me on gemcitabene nab-Paclitaxel in 2 weeks. I understand the side effects of this cocktail will be worse than the Folfirinox. And my chances of good response are getting slimmer. My oncologist mentioned a new class of drugs that will be coming out at the end of the year that target the KRAS mutation, and I may be a candidate for that. Anyone have experience/knowledge of this new treatment?