Paget's disease of the bone and other inflammatory issues

Posted by nottoday @nottoday, May 27, 2022

Anybody with PDB out there? My ALP just jumped from 70 to 110. I am having extreme ankle joint pain and swelling and other joint mild swelling/pain. I also was just told I have mediastinal adenopathy.

For those with pagets did your AP go up with other inflammatory processes?
I dont know if my pagets is coming out of remission or if the lab is triggered by the inflammation elsewhere

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nottoday | @nottoday | May 27, 2022

A few months ago I had a high CCP with sore joints. I was told that because the sed rate wasnt high and the RA factor was not present that I didnt have RA.
Now months later I have extreme joint pain and swelling. I went to the ed for torodol and steroids and they did a CT because of dry cough ( I thought it was allergies)
I was told I have mediastinal adenopathy. I was sent to an oncology navigator and I am waiting for a biopsy.

I now have high d-dimer and CRP. And the sed rate went up from <10 to 20. My ankles are so sore I cannot walk and swollen I cannot put my shoes on. Elbows and wrist are not as bad but I feel it.

Has anyone had this experience? I wonder if my adenopathy was initiated by undiagnosed RA or if the inflamed joints are secondary to the adenopathy.