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P1NP number on Tymlos

Posted by marymj7 @marymj7, Jan 1, 2024

After 3 months on Tymlos, my P1NP bone marker has increased by 50% to 109. I was initially excited, but am wondering if this is excessive. Anyone else had numbers like this?

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summera1 | @summera1 | 1 day ago
In reply to @mayblin "@summera1, you wrote "CTX from 046 to 665 for three months on Tymlos": was 046 a..." + (show)
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@summera1, you wrote "CTX from 046 to 665 for three months on Tymlos": was 046 a typo? If not, were you on a bone drug at that time?

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@mayblin Oh, my! yes a typo! THANKS!
CTX went from 946 to 665. Do you know how I can edit my post?

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summera1 | @summera1 | 1 day ago
In reply to @summera1 "@lurawilson Thank you for your kind reply:) My p1NP went from 74 to 119 and CTX..." + (show)
Profile picture for summera1 @summera1

@lurawilson Thank you for your kind reply:) My p1NP went from 74 to 119 and CTX from 946 to 665 for three months on Tymlos. I get a DEXA in two months. I would like HRT if it helps bone, but trying to see if hyperthyroidism or high LDL levels would be affected. I was on bioidentical topical (thigh) cream with estrogen/progesterone combo and felt wonderful. They made me stop after ten years, but now they seem to be allowing it again. However, I stopped taking them about ten years ago and now they saw I can't start again because it has been too long. My doctors don't seem to want to give me HRT but I am still researching. What HRT form do you use? Pros/cons? Any advice on convincing my doctors?

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@summera1 EDIT: CTX 946 to 665

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mayblin | @mayblin | 1 day ago
In reply to @lurawilson "@mayblin Thank you, I am really thrilled with the improvements in my hips as well! To..." + (show)
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@mayblin Thank you, I am really thrilled with the improvements in my hips as well! To answer your questions, yes, I am still on the HRT regimen: 100 mg progesterone daily and the 0.0375 mg estradiol patch changed twice a week. My most recent bone turnover markers from June were:P1NP: 89 CTX: 493

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@lurawilson, i appreciate you sharing your experience. The BTM looking good! Wishing you continued success!

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mayblin | @mayblin | 1 day ago
In reply to @summera1 "@mayblin Oh, my! yes a typo! THANKS! CTX went from 946 to 665. Do you know..." + (show)
Profile picture for summera1 @summera1

@mayblin Oh, my! yes a typo! THANKS!
CTX went from 946 to 665. Do you know how I can edit my post?

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@summera1
Thanks for the clarification!

To edit a post, hit the 3 little dots in the bottom right corner then click "Edit" - you have about a couple hours (i think?) to make changes. After that, you can either reply your own post with the correction, or hit the 3 dots and choose "report comment" to ask a moderator to fix it for you.

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