oxycodone vs duloxetine

Posted by rmbrandt @rmbrandt, Jun 28 3:24pm

I have an autoimmune disorder that has caused many problems, most recently pleural effusion, that is fluid in the sac surrounding my right lung. Since this began in February, a liter of fluid has been drained from my body 3 times a week. I am also on 80 mg of Furosemide twice a day to deal with fluid build up throughout my body. There can be a lot of pain associated with all this. I was on a small amount of Oxycodone, 2.5 mg/ 2.5% solution every 6 hours. Pain Center doctors believe this is an appropriate treatment. However, my PCP does not want me on Oxy so he prescribed Duloxetine, starting at 20 mg once a day. Although that's a low dose, I think I have had a strong reaction. I already have Cervical Dystonia, but since taking the Duloxetine, there is a lot more stiffness developing in my neck, back, jaw... Also, a rash has developed in the area of the drainage catheter. Another factor in considering any treatment is that I am 79. Duloxetine is questionable in treating elderly and concerns about opioid addition become much less relevant. So I'm mainly looking for thoughts on the use of Duloxetine in my situation, its effectiveness and possible side effects. Thoughts on Oxy use would also be appreciated. Thanks.

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Profile picture for jshuchart @jshuchart

Sorry to say I take both drugs. The Oxy dosage is 15mg 4x/day. Neither drug though helps. I have Complex Regional Pain Syndrome and my pain level in my left foot is 9 and 7 in my right. I continue my search for the needle in the haystack, some treatment I haven't tried that someone out there has found. Good luck to you!

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@jshuchart I’m a medical marijuana patient and it helped my lower back at times. I use a topical cream. That might help your feet. Also, my neck was fused in February and the pain has been terrific. I was told about Aspercreme for nerve pain and it worked to stave off tremendous headaches I get from my neck. Since it treats nerve pain rather than muscle pain, you might give that a try. Good luck partner in pain.

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