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osteoporosis, calcium supplements and calcium paradox
Hello, I am prescribed to take alendronic acid with vitamin D3 for my osteoporosis. I take also calcium 1000mg for a long time. However, I have also high cholesterol (about 6,9) and I wonder about negative effect of such medication on my blood vessels. I have searched the literature and found that osteoporosis itself can cause calcification of vessels. Calcium supplements are found in some articles to cause the progression of aorta calcification. So, the question is if your doctors are recommending you to take calcium supplements or not?
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I developed a large kidney stone while on Tymlos. The stone was large enough that it had to be surgically removed. One of the warnings for Tymlos is possibility of kidney stones, and high blood calcium levels. I feel like my blood calcium levels should have been followed while I was on the treatment. I refused the drugs with the potential jaw necrosis side effect. I don't think there are any good options, but I would really be concerned about Tymlos since you have a problem with calcium deposits.
Thank you! Good to know.
Can you send a link to the literature you found saying that osteoporosis itself can cause arterial calcification? That’s news to me. That sounds very scary. I started Vitamin K-2 with MK-7, the approved type for directing calcium into the bones and not the arteries. I am familiar with the research in K-2 and have read the Calcium Paradox. However, I don’t understand how osteoporosis, where the bones are losing bone faster than building it up can cause arterial calcification. Can you explain that, please? That’s the last thing I want to hear today! Uggh...
It is true that there is a link, but they don't know why. Probably a good idea to discuss with a cardiologist and have whatever tests he recommends for cholesterol, artery health, etc.
https://pmc.ncbi.nlm.nih.gov/articles/PMC4422187/#:~:text=Cardiovascular%20calcification%20is%20a%20widespread,a%20common%20cause%20with%20it.
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3 ReactionsI'm hoping the statins I take are taking care of my arteries. I am also starting on K2 with D4. As a vegetarian I also take B12 along with prescribed meds. At nearly 80 I need all the help I can get for my fragile bones
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1 ReactionThank you for that link. That sounds rather scary to me, though I am taking Vitamin K-2. I only skimmed the article as I am overdue for making my lunch, but THANK YOU for sending me the link! I've emailed it to myself to read in full at a better time. I do see a lipidologist next week, as a matter of fact, so I can ask him what he knows about it!
I would like to add this recent study adding to understanding how mechanisms of calcification of bones and vascular calcification (VC) are linked.
https://ec.bioscientifica.com/view/journals/ec/12/11/EC-23-0305.xml
It has been shown earlier that supplementation with vitamin K2 can have a protective effect on VC.
I take 100 mcg of vitamin K2 and hope that it will protect me.
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1 ReactionHello,
I just wondered if statins can be taken by patients with OP and if statins interact with osteoporosis medicines. What is your doctors' opinion?
I too have a high cholesterol but am hesitant to take statins,
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1 ReactionCan you tell me what you mean by the approved type of K-2 and MK-7? Also what brands do you take?
Thank you very much!
.....I started Vitamin K-2 with MK-7, the approved type for directing calcium into the bones and not the arteries.
I take both Tymlos and a statin. There are no issues, and no interactions to worry about. I've done great with Tymlos, and statins have lowered my LDL to 60. Both my cardiologist and my endocrinologist are well aware of the meds I am taking.
Don't be afraid of statins. They are really miracle drugs. Nothing you do apart from becoming a vegan is going to lower your LDL as much as a statin.