Orgovyx and Zytiga combined
I’m preparing for proton radiation therapy at UFHPTI (Jax). Was all nice and tidy with containment to the prostate only. Did a final PET scan to be sure no metastasis and found 7 lymph nodes on both sides of my pelvis and lower abdomen. So now my tidy has changed to an un tidy aggressive cancer w metastasis. Changed my proton therapy from 6 weeks followed by ADT (orgovyx) for 6 months - to: 6 weeks of Orgovyx plus Zytiga , followed by 8 weeks of proton radiation , and staying on both drugs for 2 years. YUK.
Can any of you guys tell me if you have had these two drugs together and how you tolerated it ? Trying to understand what to expect for these two years. I’m 71
Thanks, Tom
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Same problem they don t trust anything that doesn’t have 5yr or longer studies. Orgovyx was only fda approved Jan 22. Long studies don’t exist yet . I’m on orgovyx/Zytiga only side effects fatigue and sweat a bit more. Orgovyx took my psa to undectable in 3wks still umdectable@months. Cautionary tale xytiga only seems to exist as generic abiriteroneacetate. Use 250x4 vs 50mgx2 huge ripoff in pricing on 500mg
Don t have Lupron experience but this forum tells of leg pain and long time recovering testosterone
Thank you for taking the time to write. I sincerely appreciate it. Have you checked out Mark Cuban‘s pharmacy for the pricing? 4×250 mg appears to be about $134 a month.
costplusdrugs dot com
Best wishes for success in your fight!
I heard that Cuban gives drug grants each year up to a certain number. Does he do that through his pharmacy ? Xytiga/arbiter one costs my insurer 14k monthly with a$146 copay. The 500mg has a $1370copay which got my attention.
I can’t answer the question regarding grants however I know that the actual price that he charges for generic abiraterone acetate 100 250 mg pills is $134 without insurance.
On orgovyx/zitiga 13 months Gleason 9 nodal involvement psa undectable since 3rd wk testosterone less than 10. Sort of out of fresh ideas . Went to consult Dr Kwon he said this about the drug combo “nicely aggressive “. So my oncologist and he concurred on your drug combination .
On orgovyx/xytiga 13months psa undectable after 3wks . Testosterone 10. Went to consult Dr Kwon he commented that the combo was”nicely aggressive “So he and my oncologist concurr on that.
We used Mayo Clinic Specialty Pharmacy for Zytiga and they always dispensed the Zytiga in 250 mg, four tablets to be taken every day with prednisone It should be easy to get generic Zytiga, which is abiraterone, in 250mg, pretty much anywhere as that seems to be SOC.