Orgovyx and the timeline for return of normal testosterone level

That reflects my thoughts as well. Let the Testosterone recovery time be factored in with ADT (stop ADT earlier if recovery time is longer). Get good scans (maybe multiple types), test & understand your particular cancer cell genetics; then see if you can go after them with targeted methods and/or multiple treatments. Never just blindly accept treatment without understanding the reasons and options - questions like these are great! Thanks,

6 months on Orgovyx and now 7 weeks off my testosterone has not risen at all I am at a 10.7
Dr. is quite surprised and will be getting another blood test today or tomorrow

It sounds as if your persistent PSA requires continued treatment. Not an oncologist so can’t say what next steps should be done, but going off ADT could be premature….JMO

I was only on ADT for 4 months. My first testosterone test showed 1.62. My second on Dec 24’ showed 401 which is mid normal range.
My libido is still an issue and becoming frustrated although I am starting to get better blood flow and a bit better desire after taking Cialis daily. Most of the other side effects have subsided.
Hot flashes
Weight gain
Moodiness.

How far apart were your first and second T tests? 3 months or 6 months? Thanks.

I'm currently on Lupron and will ask to switch to Orgov. for my second 3 months of 6 months treatment. Orgov. has a faster rebound speed than Lupron. I would consider 184 within 3 months positive and personally won't touch T supplements as they are psa rocket fuel. My therapy start point was T-250 which is considered low T and was a huge win for G-9 Grade 5 cancer.

3 mos

I doubt any Dr would actually want us doing T therapy as it is cancer fuel. 30 minutes is considered minimal exercise. My routine at 71 is a 45-minute spin class with approx.. cal burn of 450 followed by 45 minutes or so of weightlifting with total 550-600 cal burn. And if weather allows, another 450-500 cal burn of bike riding either on mtb trails or neighborhood trails. My normal calory intake is between 1600-2200 per day and as one the is prone to weight gain but recently losing 32 pounds I monitor my calory intake and burn using the Noom app and a heartrate monitor. My goal is to attempt to minimize weight gain during ADT. My doctor wants me to keep officiating lacrosse during treatment. I looked at him like he had a third eye lol. Said cardio problems are rare on short term ADT. Best wishes on your recovery and journey.

My lead RO referred me to a (fertility specialist) urologist saying there would be little risk, given active monitoring, for T supplements. He's nationally known and has 40 years of experience, hence, I trust him more than most. Surprisingly, my much more conservative younger RO Dr. made the same recommendation saying, "several of her patients have done well with the supplements" and a third RO concurred. I'm not rushing into anything and will consider all these doctor's opinions and well as yours.

I've had 4 continued ADT (Orgovyx 4 months) side effects after one year: hot flashes, moderate ED, lower strength/energy, belly fat. I also exercise daily and have a personal trainer to help out. Dialing back the side effects is highly desirable for me, if I don't take on unacceptable risk. I realize we are all different and our risk/reward approaches should take that into consideration. Postings and discussions like this help me and others evaluate what is best to keep PCa in remission and enjoy our lives as much as possible.