Octreotide or Lanreotide

Many patients do have input into the choice between lanreotide and octreotide, so it is absolutely reasonable to discuss your preference with the doctor.

Both are standard SSA treatments for Grade 1 small bowel NETs and work very similarly for tumor control and symptom management.

In general:

Lanreotide is a deep subcutaneous injection (under the skin) and many patients find it more convenient.
Octreotide LAR is an intramuscular injection and sometimes requires a longer clinic visit and more preparation.

Some doctors prefer one based on:

Their experience
Insurance coverage
Injection center logistics
Specific symptoms or tumor behavior

But in many cases, patient comfort and convenience are part of the decision.

UCSF NET specialists deal with this all the time, so it would be very reasonable to simply ask:

“Is there any reason lanreotide would not be a good option for him?”

Many patients with slow-growing Grade 1 NETs do very well on SSA therapy for years.

I started with Lanreotide, but I also have carcinoid syndrome, (Hot Flashes) and it did not control them. Tried Ocreotide and that was successful in controlling the symptoms.. I'm not sure what the choice is based on..

@vinnie694

Thanks for detail.

@mcharlesfrancis

Thanks so much and good timing as call is today with doctor.

I’ve had both drugs as our hospital recently switched, either due to availability or to save money. The octreotide shots are much quicker but seem to cause more residual hip pain (bigger needles I was told).

@zacharycat

Thanks amazing how variable this cancer is and each person’s response to treatment…kind of crazy making to try to figure out

@carrie567 Hi and welcome to Mayo Connect. You have learned why this cancer, and all cancers for that matter, are so difficult to treat and cure. Everyone's body is different, so each body can respond differently to the same treatment. Good luck with your doctor call today. Please let us know how it goes, ok?