No longer a tourist. I’m in the club.

Posted by Goodvida @malligood, Sep 30 4:28pm

Just got my biopsy results yet. Otherwise I’m in the best health of my life. 70 years old . PSA 6

Prostate, left mid, biopsy:
– Prostatic adenocarcinoma, Gleason score 3+4=7, Grade group 2, involving 1 of 1 core and 30% of the submitted tissue.
– Perineural invasion is present.

C. Prostate, left base, biopsy:
– Prostatic adenocarcinoma, Gleason score 4+4=8, Grade group 4, involving 1 of 1 core and 20% of the submitted tissue.

M. Prostate, ROI #1, biopsy:
– Prostatic adenocarcinoma, Gleason score 4+3=7, Grade group 3, involving 3 of 3 cores and 20% of the submitted tissue.
– Perineural invasion is present.

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mjp0512 | @mjp0512 | Sep 30 4:42pm

Sorry you had to dive into the club. When is your PSMA PET scan scheduled?

wheel1 | @wheel1 | Sep 30 5:09pm

Get them to submit your biopsy tissue for Decipher right away!

Jeff Marchi | @jeffmarc | Sep 30 5:41pm

The Gleason 4+4. is really the one that makes it more aggressive. The lower numbers do not really matter for treatment decisions.

Perineural invasion is very common, It’s one of the few things you don’t really have to worry about.

4+4 is very treatable with radiation or surgery.

topf | @topf | Sep 30 5:47pm

Sorry to hear that you were given membership. As has already been said, with a 4+4, you should get a psma and a decipher. I would also submit the biopsy to Hopkins for a second reading. It seems there is no mention of cribriform or intraductal, which is good.
Many 4+4 at biopsy get downgraded at pathology. That happened to me, from 4+4 to 3+4.

diverjer | @diverjer | Sep 30 9:32pm

Sorry you have those results, but at least no cribriforms or SVI. Also, really not that many positive samples. I don't think it looks bad for biochemical recurrence (BCR)? However I am new at this, but that is my thoughts.

wheel1 | @wheel1 | Sep 30 9:58pm

Likewise, i had one Gleason 8 (4+4) at biopsy and it was downsized to Gleason 7 (4+3) at post surgery pathology. My initial biopsy had three 6’s and 2 favorable 7’s and that one 8.

TurtBean | @turtbean | Oct 1 7:40am

Another one who was downgraded after pathology (3+5 intermediate unfavorable downgraded to 3+4 intermediate favorable), so take a breath, hold it, and let it out nice and easy, you’ve got this.

stew80 | @stew80 | Oct 1 9:28am

Welcome to the club (that you would prefer not to be part of I'm sure). Hopefully the interaction on the forum will help you to navigate this journey. You are not alone.

jayhall | @jayhall | Oct 1 3:17pm

I'm sorry you had to join the club. This group is amazing and I'm lucky to have found this forum I don't think I could have gotten through my Cancer Diagnosis/Surgery and Journey without this group. Keep on posting here! We are here for you.

johnnyz | @johnnyz | Oct 2 6:23am

You are in a great club of people who really do help others. I have been involved for almost 3 months and can say that the advice and quickness to respond has been incredible. I am sure that without this group, my stress would be much higher. It’s kind of like crowd sourcing; you can elicit stories that are tailored to your concerns. Any who, sorry about your results and wish you the best…take care