I am a 63 yr old female, active and in otherwise excellent health, who ended up recently being admitted to the hospital with ischemic colitis. A CT scan revealed a blood clot in the portal vein of my liver. Further testing revealed both Factor V Leiden and Lupus Anticoagulant clotting anomalies. I am now faced with lifelong daily Warfarin treatment. My hematologist has removed my daily Meloxicam (anti-inflammatory), taken for sciatica and spinal stenosis, as well as all over-the-counter NSAIDs. I have read that some patients on Warfarin have successfully combined it with Celebrex, and I am wondering if anyone on this discussion may have info. My hematologist is skeptical, but my back and loss of ability to engage in mild sports activities (golf, cycling) makes me want to find a solution.