Newly diagnosed PBC-

Posted by lbo615 @lbo615, Mar 5, 2023

I’m starting Ursodiol tomorrow. I’m a little worried about the side effects. Anyone experience weight gain or other side effects from this med?

Interested in more discussions like this? Go to the Autoimmune Diseases Support Group.

I was having some stomach issues, itching (which I didn’t know was a liver thing), on and off high alt, ast and ggt, fatigue, hypokalemia and my cholesterol spiked up high after always having low.
The AMA antibodies are specific for PBC but CAN be indicative of other things. The liver biopsy confirms. This is what my dr told me.
Have you seen a gastroenterologist? They may recommend liver biopsy.

REPLY

I responded to your reply and question but I must have put it in my post under PBC. Now it won’t let me copy it here.

REPLY
@lbo615

I was having some stomach issues, itching (which I didn’t know was a liver thing), on and off high alt, ast and ggt, fatigue, hypokalemia and my cholesterol spiked up high after always having low.
The AMA antibodies are specific for PBC but CAN be indicative of other things. The liver biopsy confirms. This is what my dr told me.
Have you seen a gastroenterologist? They may recommend liver biopsy.

Jump to this post

I’m having a biopsy of the skin where the Livedo reticularis is. That can be a symptom of many autoimmune and vascular diseases and even cancers.

REPLY

Hello,

I did not have symptoms . 30+ years ago I visited my doctor for a general checkup. I had some lab work done and he noted that the tests showed elevated areas that called for further testing LIKE a biopsy. So the biopsy was done with the result of PBC. I’m fortunate that most of my life PBC was pretty mute. However it’s not so mute today but still tolerable.
Karen

REPLY
@lbo615

I was having some stomach issues, itching (which I didn’t know was a liver thing), on and off high alt, ast and ggt, fatigue, hypokalemia and my cholesterol spiked up high after always having low.
The AMA antibodies are specific for PBC but CAN be indicative of other things. The liver biopsy confirms. This is what my dr told me.
Have you seen a gastroenterologist? They may recommend liver biopsy.

Jump to this post

Hi Lady,

The sooner you are prescribed urso and other meds to help with the itching and cholesterol the better for you. I would get a second opinion on the biopsy.

Karen

REPLY
@lbo615

AMA M2 antibodies and a liver biopsy for me. Also other liver enzymes were elevated

Jump to this post

how are you doing after a year on Ursodiol?
It's been a year for me but recently had the liver enzymes a little bit elevated.. It was normal for about nine months.
Thank you!

REPLY
Please sign in or register to post a reply.