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New Member

Posted by swl1956 @swl1956, Apr 8 1:26pm

Greetings! I've just joined here due to the American Cancer Society's CSN (Cancer Survivors Network) forum has announced they are terminating their website. It was a good one and I found it very helpful during my Pca journey thus far. I'm hoping the Mayo Clinic's site will be as good or better? Quick background; diagnosed fall 2023 with Gleason 4+3=7. Two biopsies confirming. Had MRI, bone scan, PSMA PET scan, and Prolaris genetic test all of which concluded no spread outside of gland. Was told I was a good candidate for focal therapy due to single lesion and in an optimal position. So I chose IRE Nanoknife procedure which was successful confirmed by imaging and biopsy however six months later PSA rose and another PSMA PET scan indicated activity in the pelvic lymph nodes. This initiated more treatment of 40 sessions pelvic IMRT total 80gy and taking Orgovyx and Zytiga for a prescribed 24 months. I'm a little over a year into the ADT and my PSA is .05 over the past few tests. The ADT with second gen Zytiga is beating me up a bit. I'm hopeful I'll start feeling better when this regimen finally ends and hope that it's been effective enough to keep my Pca in remission for a while?
Anyhow, I'm hoping I'll be welcome here.

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

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Jeff Marchi | @jeffmarc | Apr 13 7:21pm
In reply to @cadaddy "@jeffmarc Is there a reason post-ADT not to take a drug that increases testosterone production? It..." + (show)
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@jeffmarc
Is there a reason post-ADT not to take a drug that increases testosterone production? It seems like it could be helpful but I'll assume there are reasons not to do it.

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@cadaddy
Most oncologist will not be happy with you doing this unless you’ve got many years undetectable. The problem is testosterone can feed the cancer and get it growing again. Even if somebody is castrate resistant, part of their cancer is not and is going to start to come back again. If you’ve only been undetectable for a year or two getting testosterone injections, could really bring back the cancer.

There are techniques where people get large doses of testosterone to make their cancer start to die. When your cancer becomes resistant and starts to grow even without testosterone, a large dose of testosterone can actually kill off the resistant cancer cells. So there are cases where you can do this, but it can’t be on a regular basis for most people that have had prostate cancer.

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Moderator
Colleen Young, Connect Director | @colleenyoung | Apr 19 4:39pm

@swl1956, I'll add my belated welcome. Allow me to "show" you around a bit.

Use Search (https://connect.mayoclinic.org/search/) to find discussions related to your questions or topics where you may have experience to add. You can limit your search to prostate cancer related topics only by going to the Prostate Cancer group here: https://connect.mayoclinic.org/group/prostate-cancer/

You might also want to follow the expert blog on
- Men's Health https://connect.mayoclinic.org/blog/mens-health-1/

Community Guidelines https://connect.mayoclinic.org/blog/about-connect/tab/community-guidelines/

Find tips about getting started on Mayo Clinic Connect in the Help Center https://connect.mayoclinic.org/help-center/

Feel free to let the guys and their supporters on the soon to be closed Cancer Survivors Network (ACS) that they can hop over to Mayo Clinic Connect and stay connected with each other and make new connections. That's a lot of CONNECTing 🙂

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