Negative sputum results without treatment

Posted by sayaboleh @sayaboleh, May 12, 2019

Has anyone had spontaneous sputum conversion without taking the big 3? I was told recently that my latest samples produced no pathogens — i.e. MAC organisms. That is great news of course — I had no idea that would happen but found some studies that 40- 60% can spontaneously convert without the benefit of treatment. I was diagnosed about 8 years ago and just assumed I would always have it. I have had no symptoms other than a flare up recently when I caught a cold, hence the sputum samples to figure out what was going on. I was given a long explanation by my pulmonologist which was a little difficult to follow. Would love to hear from others if they know anything about this.
Mary

@janovr

🎉🎉🎉🎉I have just received the BEST PRESENT EVER!
NO MAC IN MY LAST SPUTUM CULTURE!
Thank you Jesus for my healing as I stopped the BIG 3 MEDS, 4 years ago after only 3 months due to SEVERE SIDE EFFECTS of losing 40 lbs. in that short period of time!
Jan/Fl!

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@janovr
That's wonderful news!!!

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@windwalker

@sayboleh Hi Mary. So GLAD you are mac-free!

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thanks Terri. I think we could all do with some good news now and then. I will be at the NTM conference on Friday and will report back if I hear anything new and exciting.
Mary

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@janovr

🎉🎉🎉🎉I have just received the BEST PRESENT EVER!
NO MAC IN MY LAST SPUTUM CULTURE!
Thank you Jesus for my healing as I stopped the BIG 3 MEDS, 4 years ago after only 3 months due to SEVERE SIDE EFFECTS of losing 40 lbs. in that short period of time!
Jan/Fl!

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Congratulations! He is the great healer!

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Hi all
I just wanted to post this article on Mogradex
It's in the pipeline with testing being done for NTM patients to use with or without antibiotics.
It enhances your own immune system without the the toxic side effects of antibiotics.
Have any of you heard about this? It is another to keep our eyes on like the nitric oxide treatment.
Here is a link
http://boston.big3bio.com/2018/04/02/spotlight-qa-rob-neville-ceo-savara-pharmaceuticals/
Here is part of the article:

Molgradex is an inhaled formulation of recombinant human GM-CSF. GM-CSF is not an antibiotic. Rather than targeting bacteria directly, GM-CSF stimulates the innate immune system in the lungs. The attraction of this approach is that we expect it can be used both with or without antibiotics and that the mechanism will not be affected by antibiotic resistance by the bacteria.

What do study results indicate so far?

Neville: In animal studies, GM-CSF has been shown to kill NTM with similar efficacy compared to commonly used NTM antibiotics, and the simultaneous use of GM-CSF with antibiotics may further improve the antibacterial effect.

Shari

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@pfists

Hi all
I just wanted to post this article on Mogradex
It's in the pipeline with testing being done for NTM patients to use with or without antibiotics.
It enhances your own immune system without the the toxic side effects of antibiotics.
Have any of you heard about this? It is another to keep our eyes on like the nitric oxide treatment.
Here is a link
http://boston.big3bio.com/2018/04/02/spotlight-qa-rob-neville-ceo-savara-pharmaceuticals/
Here is part of the article:

Molgradex is an inhaled formulation of recombinant human GM-CSF. GM-CSF is not an antibiotic. Rather than targeting bacteria directly, GM-CSF stimulates the innate immune system in the lungs. The attraction of this approach is that we expect it can be used both with or without antibiotics and that the mechanism will not be affected by antibiotic resistance by the bacteria.

What do study results indicate so far?

Neville: In animal studies, GM-CSF has been shown to kill NTM with similar efficacy compared to commonly used NTM antibiotics, and the simultaneous use of GM-CSF with antibiotics may further improve the antibacterial effect.

Shari

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@pfists Shari, That is very exciting news. It sounds promising!

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@pfists

Hi all
I just wanted to post this article on Mogradex
It's in the pipeline with testing being done for NTM patients to use with or without antibiotics.
It enhances your own immune system without the the toxic side effects of antibiotics.
Have any of you heard about this? It is another to keep our eyes on like the nitric oxide treatment.
Here is a link
http://boston.big3bio.com/2018/04/02/spotlight-qa-rob-neville-ceo-savara-pharmaceuticals/
Here is part of the article:

Molgradex is an inhaled formulation of recombinant human GM-CSF. GM-CSF is not an antibiotic. Rather than targeting bacteria directly, GM-CSF stimulates the innate immune system in the lungs. The attraction of this approach is that we expect it can be used both with or without antibiotics and that the mechanism will not be affected by antibiotic resistance by the bacteria.

What do study results indicate so far?

Neville: In animal studies, GM-CSF has been shown to kill NTM with similar efficacy compared to commonly used NTM antibiotics, and the simultaneous use of GM-CSF with antibiotics may further improve the antibacterial effect.

Shari

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@pfists Thanks for that info, fingers crossed!

REPLY
@pfists

Hi all
I just wanted to post this article on Mogradex
It's in the pipeline with testing being done for NTM patients to use with or without antibiotics.
It enhances your own immune system without the the toxic side effects of antibiotics.
Have any of you heard about this? It is another to keep our eyes on like the nitric oxide treatment.
Here is a link
http://boston.big3bio.com/2018/04/02/spotlight-qa-rob-neville-ceo-savara-pharmaceuticals/
Here is part of the article:

Molgradex is an inhaled formulation of recombinant human GM-CSF. GM-CSF is not an antibiotic. Rather than targeting bacteria directly, GM-CSF stimulates the innate immune system in the lungs. The attraction of this approach is that we expect it can be used both with or without antibiotics and that the mechanism will not be affected by antibiotic resistance by the bacteria.

What do study results indicate so far?

Neville: In animal studies, GM-CSF has been shown to kill NTM with similar efficacy compared to commonly used NTM antibiotics, and the simultaneous use of GM-CSF with antibiotics may further improve the antibacterial effect.

Shari

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@pfists Thank you posting this Shari. This does sound promising, lets pray it works!

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@sayaboleh

thanks Terri. I think we could all do with some good news now and then. I will be at the NTM conference on Friday and will report back if I hear anything new and exciting.
Mary

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@sayaboleh Hi Mary. That is great that you are going to the NTM conference this year. Another member, @deborahwolf, is also going to be there. You two should try to meet up while you are there. I hope you gals come back with some new info and update us on what might be coming down the pipeline.

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@marilyns

Congratulations! He is the great healer!

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@marilyns AMEN!

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Waiting and hoping some one will post info on the conference Friday,

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My CT scan show multi areas of bronchiectasis with many nodules. They are doing sensitivity test to determine what med to give to me. I didn't have much symptoms until recent pneumonia. Now I hear wheezing sound when I breath and I am just so tired making it difficult for me to work 5 days. Reduced the work days to 4 days a week. Wondering if it would be better to take early retirement at 62 to focus on my health.

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@poppins

Waiting and hoping some one will post info on the conference Friday,

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@poppins Hi. We have two members that I know of that are at the conference. They said they would check back with us and share what they learned.

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