Need advice regarding relapsed Burkitts lymphoma treatment

Posted by mayurpatel @mayurpatel, Aug 22 2:21pm

My brother (24 M) has been diagnosed with relapsed Burkitts lymphoma. For the 2nd line of treatment our oncologist treated him with one cycle of POLIVY+ICE+THEOTEPA and did a bone marrow biopsy which showed less than 1% cancel cells remaining in his bone marrow. But his PET scan showed some patches in his Sinus and back. He is now moving forward with Glofitamab (COLIMVI) as a bridge to remission and once remission is achieved, he will go for stem cell transplant.

Just to be sure, I also consulted another oncologist regarding the treatment plan. His idea was to give one cycle of intense Chemotherapy to bring him into remission instead of Glofitamab as it is not very effective for Burkitts. And once remission is achieved even he will go for stem cell transplant.

I needed some advice regarding the effectiveness of Glofitamab in this case. Should we go with it or a cycle of intense Chemotherapy?

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beachlvr | @beachlvr | Aug 23 10:12am

I’m so sorry to hear this. I am still in treatment for Burkitt Lymphoma. I’m terrified of it coming back already and I’m not even done treatment yet! Where is your brother getting treatment? It’s crazy how much research and advocating we still have to do for ourselves isn’t it? I am praying for your brother and hopeful this second line treatment does the trick!

mayurpatel | @mayurpatel | Aug 23 1:39pm

In reply to @beachlvr "I’m so sorry to hear this. I am still in treatment for Burkitt Lymphoma. I’m terrified..." + (show)

@beachlvr we are based in India. We constantly have to look for case studies and different combinations of therapy as there is no standard 2nd line of treatment. Hope your treatment goes well and you recover as soon as possible.

beachlvr | @beachlvr | Aug 23 2:04pm

Your brother is so lucky to have you 🩷🙏🏻

katgob | @katgob | Aug 23 11:00pm

I wonder which oncologist is at a research type hospital that specializes in blood cancers? I truly hope one is. I did not have that blood cancer but MDS.
I am hoping you checked the subject bar to see if more have this cancer? I know moderators post at some point. I pray both of you find a treatment that you are confident in once you speak to your medical teams. These is no doubt blood cancers are not easy.

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