My TRIMIX experience

Posted by maverick75 @maverick75, Jan 4 9:27am

I've been using Trimix for about six months with outstanding results. It did take some experimentation to figure out the best way to make it work for me. With hopes that it may help others, here's what I discovered using this medication: (BTW, I'm 71, one year post SBRT and 4 months Orgovyx)
- I have had to use the oral antidote several times (works well) in the early dose experimentation days for super hard erections lasting more than three hours (4tablets of 30 mg pseudoephedrine. Don't make the mistake of buying the extended release pseudoephedrine tabs). Make sure you have this on hand before you start this medication!
- I had to find the sweet spot for the injection site and depth. For me turns out to be the 10 and 2 o'clock position with the 1/2" needle almost fully inserted around mid-shaft.
- Shelf life on the Trimix in the refrigerator is limited. I can definitely see a difference in the results at the 3-4 week period. For me, it became pretty useless after 4 weeks, even at a higher dose. To help extend the life, I now fill all syringes with the needed dose as soon as I get the medication and immediately place all syringes into the freezer until needed. Now, I take a syringe out about 30 min before needed and it's ready to go. This is working well and my pharmacist said this should extend the shelf-life to 6 months or more.
- After injecting, massage the entire penis and base to help distribute the medication throughout the muscle structure. This will help significantly.
- Stand for the first 5-10 minutes after injection as gravity aids in the blood flow into the penis.
This medication has been a lifesaver for me. I was afraid I'd never see a useful erection again. Now, I'm back to 18 in that regard-- actually better than 18 as my erection stays hard even after an orgasm! Best of luck guys! Be aware that your partner may hide your medication if you use it to often. (-:

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@dm1451

I’m considering penile injection for ED. Dr. would prescribe Tri-mix. I’m seeking input from others who have used or explored this treatment option. From experience, how effective has it been and what are side effects/precautions?

Jump to this post

Someone else made the below comments which are pretty comprehensive. Maybe the original poster can take responsibility.

I've been using Trimix for about six months with outstanding results. It did take some experimentation to figure out the best way to make it work for me. With hopes that it may help others, here's what I discovered using this medication: (BTW, I'm 71, one year post SBRT and 4 months Orgovyx)
- I have had to use the oral antidote several times (works well) in the early dose experimentation days for super hard erections lasting more than three hours (4tablets of 30 mg pseudoephedrine. Don't make the mistake of buying the extended release pseudoephedrine tabs). Make sure you have this on hand before you start this medication!
- I had to find the sweet spot for the injection site and depth. For me turns out to be the 10 and 2 o'clock position with the 1/2" needle almost fully inserted around mid-shaft.
- Shelf life on the Trimix in the refrigerator is limited. I can definitely see a difference in the results at the 3-4 week period. For me, it became pretty useless after 4 weeks, even at a higher dose. To help extend the life, I now fill all syringes with the needed dose as soon as I get the medication and immediately place all syringes into the freezer until needed. Now, I take a syringe out about 30 min before needed and it's ready to go. This is working well and my pharmacist said this should extend the shelf-life to 6 months or more.
- After injecting, massage the entire penis and base to help distribute the medication throughout the muscle structure. This will help significantly.
- Stand for the first 5-10 minutes after injection as gravity aids in the blood flow into the penis.
This medication has been a lifesaver for me. I was afraid I'd never see a useful erection again. Now, I'm back to 18 in that regard-- actually better than 18 as my erection stays hard even after an orgasm! Best of luck guys! Be aware that your partner may hide your medication if you use it to often.
Ha ha ha ha ha ha ha ha. (Jeff’s reaction to last comment, after mistakenly turning on the mic)

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@jeffmarc

Someone else made the below comments which are pretty comprehensive. Maybe the original poster can take responsibility.

I've been using Trimix for about six months with outstanding results. It did take some experimentation to figure out the best way to make it work for me. With hopes that it may help others, here's what I discovered using this medication: (BTW, I'm 71, one year post SBRT and 4 months Orgovyx)
- I have had to use the oral antidote several times (works well) in the early dose experimentation days for super hard erections lasting more than three hours (4tablets of 30 mg pseudoephedrine. Don't make the mistake of buying the extended release pseudoephedrine tabs). Make sure you have this on hand before you start this medication!
- I had to find the sweet spot for the injection site and depth. For me turns out to be the 10 and 2 o'clock position with the 1/2" needle almost fully inserted around mid-shaft.
- Shelf life on the Trimix in the refrigerator is limited. I can definitely see a difference in the results at the 3-4 week period. For me, it became pretty useless after 4 weeks, even at a higher dose. To help extend the life, I now fill all syringes with the needed dose as soon as I get the medication and immediately place all syringes into the freezer until needed. Now, I take a syringe out about 30 min before needed and it's ready to go. This is working well and my pharmacist said this should extend the shelf-life to 6 months or more.
- After injecting, massage the entire penis and base to help distribute the medication throughout the muscle structure. This will help significantly.
- Stand for the first 5-10 minutes after injection as gravity aids in the blood flow into the penis.
This medication has been a lifesaver for me. I was afraid I'd never see a useful erection again. Now, I'm back to 18 in that regard-- actually better than 18 as my erection stays hard even after an orgasm! Best of luck guys! Be aware that your partner may hide your medication if you use it to often.
Ha ha ha ha ha ha ha ha. (Jeff’s reaction to last comment, after mistakenly turning on the mic)

Jump to this post

Thank you…. Very helpful and hopeful.

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@dm1451

I’m considering penile injection for ED. Dr. would prescribe Tri-mix. I’m seeking input from others who have used or explored this treatment option. From experience, how effective has it been and what are side effects/precautions?

Jump to this post

@dm1451, I moved your question to the discussion that @jeffmarc quoted. It was written by @maverick75.

See his post and the full discussion here:
- My TRIMIX experience https://connect.mayoclinic.org/discussion/my-trimix-experience

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I tried trimix again last night with a cialis 20 as directed. I injected 7. I got ZERO reaction. Do you think I missed the mark? I thought I hit it at 10 o'clock. Does anyone recommend an alternate solutions .. any comments will help. I am 61 years old and not going to give up.

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@paul324
I wasn't sure if I was missing the mark or the medicine needed reformulated recently and went back to doctor for him to inject to verify which. I was injecting 50 units. I was missing the mark. The doctor reformulated my medicine to increase hardness and decreased dose to 35 units.
Everything I’ve read say you aren't suppose to use trimix & pills I wonder why your dose wasn't increased.
Jake

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Missing the mark can have so many meanings. When I first started with Trimix, I had a follow-up call from the doctor at the compounding pharmacy to see how it was working. I truthfully said not all injections worked as well as others. He said that means the dosage is correct, but the administration isn't. When I assured him I was positioning the needle correctly, at the right "hour" and angle, he asked about the "dimple". Not understanding him, I asked for an explanation. He said if the syringe doesn't create a slight dimple in my penis when I inject, I'm likely not getting through the lining around the corpus cavernosum. He also advised me to vary the location of the injection along the length of my penis; that it didn't have to just be near the base. Ever since that advice, I've never had any misses.

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Mavorick if you are willing to, I forget how to do a private response, would like to chat further, I am struggling in this dept

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I had prostrate surgery 21 years ago went thru all oral medications at that time and could not keep an erection about two or three years after complete surgery I was provided with a prescription for Trimix have been using it for 17-18 years throught 2 wives and there is nothing better every thing that you sain in your post is correct and at 91 I can still hold an erection for better that an hour

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Maverick - You got great results . Myself I hate needles . So my experience was not good . Even when I did get it injected . Didnt seem to work well , it just made me sore .. Happy for you though !

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@oldbell

I had prostrate surgery 21 years ago went thru all oral medications at that time and could not keep an erection about two or three years after complete surgery I was provided with a prescription for Trimix have been using it for 17-18 years throught 2 wives and there is nothing better every thing that you sain in your post is correct and at 91 I can still hold an erection for better that an hour

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Superman Bravo

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