1. < Bones, Joints & Muscles

Muscle pain due to Statin (Praluent)

Posted by cindymattern @cindymattern, Dec 24, 2024

I took Praluent a few years ago and had really no issues. However since my knee replacement I started it again due to high cholesterol at 270. After taking a few months of shots my muscle pain got so much worse worse, top of my foot and toes, hips and buttocks, lower back and even the top of my knee hurts. I am stopping it but was reading it can take 100 days to get out of your system and I'm only about 4 weeks out. Anyone else have these issues? I have tried many statins so I was put back on this and now it's giving me issues. thanks for any input. I just want to get back to my normal for me.

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polar | @polar | Jan 1 7:04am
In reply to @polar "I can sympathize, as I have been on a Statin roller coaster myself! I started with..." + (show)
@polar

I can sympathize, as I have been on a Statin roller coaster myself! I started with a low dose of Atorvastatin, increased to a higher dose and came down with debilitating joint and muscle pain. Took a break from that and my symptoms cleared up within a few days. Later on tried a low dose of Rosuvastatin, which seemed to be tolerated, increased dosage and it felt like I was having some adverse effects. Decreased to lower dose and seemed ok. In an effort to reduce my cholesterol further, I started Praluent, in conjunction with low dose Rosuvastatin, which initially seemed ok, but as time went on, I started to feel like symptoms were coming on, so my cardiologist had me stop the Rosuvastatin and stay on the Praluent, which so far seems ok. Now I have a ruptured achilles that I am dealing with, so I have other aches and pains to worry about. Maybe my cholesterol lowering regime had some impact on that, but my cardiologist doesn't thnk so. Good luck with your issues!

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Also meant to mention that I have been taking Coq10, but hard tellin, not knowin if it actually helps.

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cantek | @cantek | Jan 1 8:27am

Statins are now implicated in contributing to dementia!

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1 reply
cindymattern | @cindymattern | Jan 2 4:33am
In reply to @polar "I can sympathize, as I have been on a Statin roller coaster myself! I started with..." + (show)
@polar

I can sympathize, as I have been on a Statin roller coaster myself! I started with a low dose of Atorvastatin, increased to a higher dose and came down with debilitating joint and muscle pain. Took a break from that and my symptoms cleared up within a few days. Later on tried a low dose of Rosuvastatin, which seemed to be tolerated, increased dosage and it felt like I was having some adverse effects. Decreased to lower dose and seemed ok. In an effort to reduce my cholesterol further, I started Praluent, in conjunction with low dose Rosuvastatin, which initially seemed ok, but as time went on, I started to feel like symptoms were coming on, so my cardiologist had me stop the Rosuvastatin and stay on the Praluent, which so far seems ok. Now I have a ruptured achilles that I am dealing with, so I have other aches and pains to worry about. Maybe my cholesterol lowering regime had some impact on that, but my cardiologist doesn't thnk so. Good luck with your issues!

Jump to this post

My cardiologist told me the same....he doesn't think it's the Praluent but when I go off it and it's been about 5 weeks I am actually feeling better....my muscles don't feel as weak and sore like they did. Even my back is feeling better. I wonder if they mess with my already arthritis that I have making the muscles hurt more. Who knows? It's definitely a frustrating roller coaster.

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charlotte12 | @charlotte12 | Jan 2 6:21am
In reply to @elizabethaames "Sadly, I have permanent damage from the rosuvastatin...they said it would 'go away' when I ceased..." + (show)
@elizabethaames

Sadly, I have permanent damage from the rosuvastatin...they said it would 'go away' when I ceased but it's been well over a year and my right leg/foot is still impaired w/muscle pain, periodic severe cramping and pins and needles as if my foot is asleep... they're trying me on pitavastatin now...kept asking for a NON-statin but insurance declines and mandates that I have to keep trying at least 2-3 others for insurance reasons, which at this rate makes me feel like a guinea pig for permanent nerve issues!

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who is the insurance? why not name them? Can you copy the response of your insurance
and publish it here? Is there any way to appeal that decision? Did you get your cardiologist
involved?

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dulu | @dulu | Jan 29 5:25am

I take COQ10 100mg for muscle pain caused by taking cholesterol meds. It's working pretty well. I get them from Puritan Pride. I stock up when they have buy one get two free sale.

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dulu | @dulu | Jan 29 5:30am
In reply to @kathleenverna "Dear Elizabeth - I am very sad to hear about your long term pain. Are you..." + (show)
@kathleenverna

Dear Elizabeth - I am very sad to hear about your long term pain. Are you taking Coq10 supplements? Maybe try acupuncture for some relief. My heart and prayers go out to you! Kathleen

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Coq10 does wonders for my muscle pain. Haven't had them for past 5 years since I started 100mg coq10 per day. I get them from Puritan Pride. I stock up when the have buy 1 get 2 free sale.

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daveshaw | @daveshaw | Jan 30 8:38am

I have been on statins for many years and I do remember my first statin gave me muscle pain. I mentioned that to my primary care physician and she switched me to Atorvastatin and my muscle pain was gone.
Anyone else taking Atorvastatin?

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2 replies
leannestork | @leannestork | Jan 30 4:15pm

Hubby started taking his at night which seemed to help a little bit. He did change medication and made a huge difference that's for sure my chat to your doctor because there is one that is known for aching and another that doesn't

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1 reply
cindymattern | @cindymattern | Jan 30 5:59pm
In reply to @leannestork "Hubby started taking his at night which seemed to help a little bit. He did change..." + (show)
@leannestork

Hubby started taking his at night which seemed to help a little bit. He did change medication and made a huge difference that's for sure my chat to your doctor because there is one that is known for aching and another that doesn't

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Sadly I've taken 4-5 different kinds. Even the Dr. didn't know what she could give me so she send me to cardiology to get the Praluent. Insurance made me try Repatha first and nope, raised my BP and sugar so they approved the Praluent. But wondering if I'm having issues with it now. I do great for about 4-6 months then start having issues.

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diana56789 | @diana56789 | Jan 31 10:09am
In reply to @daveshaw "I have been on statins for many years and I do remember my first statin gave..." + (show)
@daveshaw

I have been on statins for many years and I do remember my first statin gave me muscle pain. I mentioned that to my primary care physician and she switched me to Atorvastatin and my muscle pain was gone.
Anyone else taking Atorvastatin?

Jump to this post

I have been taking Atorvastatin for years and have had awful leg craps at night for years. I tried everything but for the last two months I've been taking CoQ10, specifically Ubiquinol 400 mg, daily. So far, nothing. I'm finally sleeping through the night! It's worth a try, I read it on here.

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