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Morning "Hangover" from mirtazapine

Posted by jgshoes @jgshoes, 3 days ago

Having brutal depressive mornings after taking only 7.5mg of mirtazapine to help sleep. Curious if anyone has experienced similar side effect.

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jgshoes | @jgshoes | 2 days ago
In reply to @skim3737 "I was on 7.5 mg mirtazapine 3 years ago, hopeful it would help my digestive system..." + (show)
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I was on 7.5 mg mirtazapine 3 years ago, hopeful it would help my digestive system and anxiety and insomnia but I had the exact same problem. Absolutely lethargic during the day from exhaustion. I went off of it because of the side effects but I did learn afterwards that mirtazapine is an unusual drug in that the tired feeling, the sleepiness effect is much stronger in a lower dose than in a higher dose. Cut to this past November and my new psychiatrist suggested trying it for my anxiety and insomnia and since I already knew that 7.5 mg was a miserable experience, I asked her if we could try 15 mg , which we did, and it's been a completely different experience. It's helping my digestion and my anxiety. It did take a few weeks for me to get used to that dose for insomnia, leading to nights of only being able to sleep in increments of 4 hours, but now I'm completely adjusted and it's been a very beneficial medication for me.

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@skim3737
Wow, thank you for the response. I went to the lower dose because if I were to get any bacterial respiratory issue mirtazapine is a contra indication to a Z pack and I thought if I had to stop it would be easier at the low dose. Will discuss with Dr.

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skim3737 | @skim3737 | 2 days ago
In reply to @jgshoes "@skim3737 Wow, thank you for the response. I went to the lower dose because if I..." + (show)
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@skim3737
Wow, thank you for the response. I went to the lower dose because if I were to get any bacterial respiratory issue mirtazapine is a contra indication to a Z pack and I thought if I had to stop it would be easier at the low dose. Will discuss with Dr.

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@jgshoes
I'm so glad that I was able to give you information that may prove helpful to you. Definitely discuss it with your doctor, although the GI doctor who prescribed it to me in 2022 either didn't know or just didn't say anything to me about the higher dose causing less daytime drowsiness. It wasn't until I researched it myself after I was already off of it that I discovered it. And now 3 years later when my psychiatrist recommended it for my insomnia in place of my previous med, I was armed with the information to try the higher dose. Good luck to you and I hope that you're able to get some answers and relief!

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