Mirabegron Prescription and getting Prior Authorization from Mayo

Posted by as737 @as737, Oct 11, 2025

My Mayo Urology PA prescribed Mirabegron over 3 months ago. As I’m retired military, I go through Express Scripts. This medication requires a Prior Authorization from the clinician. Express Scripts has told me that they have been unable to get Mayo to respond to their emails asking for justification. Has anyone else been prescribed this, and if so, were you able to get a Prior Authorization with Mayo? This is getting so frustrating because it doesn’t seem to be consistent with the care I have received thus far from Mayo.

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jime51 | @jime51 | Oct 13, 2025

In reply to @as737 "@jime51 thank you! Are you a Mayo patient?" + (show)

@as737 No. I live in the DFW area of Texas. My current oncologist is in Fort Worth, but I have a "2nd opinion" appointment at UT Southwestern in Dallas early December.

sjd4901 | @sjd4901 | Oct 14, 2025

Rather than the PA, try contacting the prior authorization department.

Colleen Young, Connect Director | @colleenyoung | Oct 25, 2025

@as737, how did this get resolved?

as737 | @as737 | Oct 25, 2025

In reply to @colleenyoung "@as737, how did this get resolved?" + (show)

@colleenyoung received a letter from Express Scripts advising that the request was denied. Strangely, it indicates that “Brand Myrbetriq “ will be approved before the generic Mirabegron. I feel that my PA should have known that.
I’m changing urologist to an MD, hopefully I will be able to get this medication if he believes it’s necessary.

lag | @lag | Oct 25, 2025

In reply to @as737 "@colleenyoung received a letter from Express Scripts advising that the request was denied. Strangely, it indicates..." + (show)

@as737 Your Mayo PA should be working closely with one or more Mayo MD urologists. It should not be hard to see a Mayo MD urologist if you say you would like to do that.

jeff Marchi | @jeffmarc | Oct 25, 2025

In reply to @as737 "@colleenyoung received a letter from Express Scripts advising that the request was denied. Strangely, it indicates..." + (show)

@as737
I got my prescription for Myrbetriq yesterday I noticed that the retail price was a little over $1600. I know that my medical provider would get the cheaper generic if it was possible,

There seem to be some legal issues with the generic version.

The generic launches were "at risk" due to ongoing patent litigation from Astellas, the manufacturer of brand-name Myrbetriq. In April 2024, a temporary injunction was issued to halt the launch of Lupin and Zydus's generic versions. By May 2025, while the litigation was still ongoing, Lupin and Zydus were permitted to expand their patent defense arguments.