MGUS and quite high Free Kappa Light Chain and Kappa Lambda Ratio

Posted by jart @jart, May 15, 2022

The above was found in his blood serum test but follow-up 24 hr urine test showed only 2 free Kappas. Has anyone had experience with this? Does the urine test supersede the serum testing? Either way, is there anything to do other than “watchful waiting?”

BTW, he also has Dysautonomia (Diabetic T2).

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I was diagnosed with MGUS three years ago and my numbers just keep getting worse. I am seeing an oncologist tomorrow who specializes in hematology malignancies. They are testing me for Light Chain Deposition Disease, a rare blood disorder. Anyone else dealing with this? Here are my numbers: Lambda Free 539.7; IgA 26; Kappa/Lambda Free Ratio .012; IgM 17; A/G Ratio 2.19; Beta Globulin less than 0.5 G/DL

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