Metastatic breast cancer: Anyone else?

I see my oncologist on Nov 8th to discuss treatment.
It’s such an odd feeling knowing I have Mets but feeling relief that it is not worse. Such a mixed bag..

My oncologist suspended chemotherapy because when blood work came back my liver enzymes were high. I am only prescribed a Keytruda drip every 21 days. I pray Keytruda destroys the cancer cells in my liver.

Welcome, @miles5513. That is good news that the cancer in your liver is reduced. Have you talked with your oncologist about the goal of chemotherapy and how long you will take it?

Just came from my surgical follow up. I have metastatic breast cancer which was confined to the 2 lymph nodes completely removed near liver area. No cancer in liver! The surgeon said I “got lucky” this was found accidently from an ultrasound in the ER for a stomach bug. There is no cancer in any other organs either! They have now turned my care over to my medical oncologists to determine treatment which may be chemo in pill form, etc but overall even though now classified metastatic can still be properly treated. I see Medical oncologist in two weeks. They said because I have been asymptomatic no telling how long it would have been before any symptoms occurred. I know I will be in treatment but feel grateful beyond measure that this was not worse.

They also stated this is still estrogen positive even though less than the original breast cancer which was 80%.
What type of treatment do they usually start you on?

This appears to be a more specific version of ER+ and the androgen receptor seems to be related to the progesterone receptor. I am not a doctor, so ask your doc. But this seems to mean you are weakly ER+ and PR-.

from Google: Estrogen receptor beta (ERβ) also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2) is one of two main types of estrogen receptor—a nuclear receptor which is activated by the sex hormone estrogen.[5]

and

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor[9] that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone[10] in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor

I received an addendum to my path report this morning stating the cancer in lymph node was weakly and partially positive for ER beta1 and negative for androgen receptor. Can someone shed some light on this for meaning? I know it means most likely coming from original breast cancer but what is beta1 and androgen receptor?
Thanks for any insight.

I have MBC, being treated with chemotherapy as cancer is in my liver. Scan showed 50% of cancer in liver is gone. I am hopeful other 50% will be gone with ongoing chemotherapy.

I am 55 was liver biopsy January 6, 2022 confirmed Mets to liver etc.

Thank you for sharing this info. Yours is quite the journey. How long have you been stage 4 and are you able to keep up with daily life? I am almost 75 and in very good health other than this latest finding of cancer. I am trying to learn all I can about living with another cancer metastisis.

I was diagnosed metastatic Estrogen & Her2 positive breast cancer in lymph nodes, sternum, spine, liver and other areas. I completed 6 chemotherapy treatments of Taxotere Herceptin & Perjeta. Am currently on Herceptin only because heart function keeps declining because chemotherapy 10 years ago cause congestive heart failure and I have been on in heart meds since 2013. I was to start Herceptin & Perjeta but Heart Ejection fraction is around 38% oncology cardiologist has me only doing Herceptin.