Medicine Sensitivity

Posted by flow65 @flow65, Jun 14, 2022

Not sure if I’m in the correct area. I seem to have medicine sensitivity. Everytime I try a new medicine especially for anxiety I have trouble. Back in 2020 when pandemic had started I stopped taking Celexa. My psychiatrist wasn’t seeing patients for awhile. It may have been laziness to stop it. It wasn’t all at once. So maybe no withdrawal effects. Then he started seeing patients. I went back to him. I tried a couple of different meds and had trouble. Went back on celexa at 20 mg got really sick. Was on different meds. Still trouble. Then was on Pristiq didn’t work. Weaned off but was too quick I believe under his direction. Then on a beta blocker. Off of that one. Then he tried to convince me going on a low dose of Seroquel. He even said I could stop it without any trouble. My husband called the pharmacist on Saturday and she said it can cause stomach upset and loss of appetite. I’m very nauseous. I stopped it on Saturday evening. I’ve been nauseous and loss of appetite for awhile. I lost weight. Had a scope and colonoscopy recently. Everything is fine there. The surgeon thinks it’s the Seroquel. I see a therapist. I’m not trusting pharmacists, drs etc. I would like to know if it’s a possibility of medications or anxiety or both. Thank you.

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@flow65, my mom is also sensitive to medications in general, especially pain medications. She often takes a lower dose than the average or typical person. @brit started a similar discussion here that you may wish to read:
- Trying to find the right medications for my depression/anxiety https://connect.mayoclinic.org/discussion/depressionanxiety/

I also wonder if you've ever had genetic testing. It could help. See the experiences and tips shared by members in discussions stated by @sallie and @ainsleigh.
- Experience with genetic testing to find the best anti-depressant https://connect.mayoclinic.org/discussion/experience-with-genetic-testing-to-find-the-best-anti-depressant/
- Why Genetic Testing for Mental Health Meds is Important https://connect.mayoclinic.org/discussion/why-genetic-testing-for-mental-health-meds-is-important/

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@colleenyoung

@flow65, my mom is also sensitive to medications in general, especially pain medications. She often takes a lower dose than the average or typical person. @brit started a similar discussion here that you may wish to read:
- Trying to find the right medications for my depression/anxiety https://connect.mayoclinic.org/discussion/depressionanxiety/

I also wonder if you've ever had genetic testing. It could help. See the experiences and tips shared by members in discussions stated by @sallie and @ainsleigh.
- Experience with genetic testing to find the best anti-depressant https://connect.mayoclinic.org/discussion/experience-with-genetic-testing-to-find-the-best-anti-depressant/
- Why Genetic Testing for Mental Health Meds is Important https://connect.mayoclinic.org/discussion/why-genetic-testing-for-mental-health-meds-is-important/

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I’m considering Genesight testing. My psychiatrist wasn’t in favor of it. Told me it’s not that accurate. I’m seeking out a provider that does Genesight testing. They told us that our insurance should pay for all of it. I hope they’re telling us the truth. If it’s a reliable company? And then to tell my psychiatrist about it. He may not be pleased. Thank you.

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As medicine resistant plus sensitive to side effects on various antidepressants genetic testing seemed like the next step in trying to better identify other possible medication options. However it was not as helpful as I would have hoped. It didn’t provide any other options.

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I’m wondering which genetic test u were given. I have the same issues, took a Genetic test, and it very clearly stated which drugs I shouldn’t EVER take, but showed many others that I could.

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@marjou

As medicine resistant plus sensitive to side effects on various antidepressants genetic testing seemed like the next step in trying to better identify other possible medication options. However it was not as helpful as I would have hoped. It didn’t provide any other options.

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The genetic testing I’m considering is called Genesight.com. It tests for psychiatric meds. Not sure if it will be helpful. Yes, what testing did you have and who and where performed it? Thanks. Flo

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It’s probably, withdrawl, you can’t just stop a medication you have to wean off.

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