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Men with breast cancer: Your experience wth hormonal therapy?

Posted by dick61 @dick61, Aug 28, 2022

I had a mastectomy and 3 positive lymph nodes and 16 proton radiation treatments at MN Mayo. I am taking 20 mg of tamoxifen. What side effects are MALES experiencing from this drug??

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dick61 | @dick61 | Jul 4, 2024
In reply to @colleenyoung "Hi @dick61 and @deebee41, here are some research papers specifically about men and tamoxifen: - Management..." + (show)
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Hi @dick61 and @deebee41, here are some research papers specifically about men and tamoxifen:
- Management of Male Breast Cancer: ASCO Guideline https://ascopubs.org/doi/10.1200/JCO.19.03120
- Survival benefit of tamoxifen in male breast cancer: prospective cohort analysis https://www.nature.com/articles/s41416-020-0857-z
- Tamoxifen in men: a review of adverse events https://pubmed.ncbi.nlm.nih.gov/27152880/

There is earlier research as well that establish tamoxifen as safe and effective in men with breast cancer.

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Thanks, Colleen. Thought I would get your interest!

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dick61 | @dick61 | Jul 6, 2024
In reply to @colleenyoung "Hi @dick61 and @deebee41, here are some research papers specifically about men and tamoxifen: - Management..." + (show)
Profile picture for Colleen Young, Connect Director @colleenyoung

Hi @dick61 and @deebee41, here are some research papers specifically about men and tamoxifen:
- Management of Male Breast Cancer: ASCO Guideline https://ascopubs.org/doi/10.1200/JCO.19.03120
- Survival benefit of tamoxifen in male breast cancer: prospective cohort analysis https://www.nature.com/articles/s41416-020-0857-z
- Tamoxifen in men: a review of adverse events https://pubmed.ncbi.nlm.nih.gov/27152880/

There is earlier research as well that establish tamoxifen as safe and effective in men with breast cancer.

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Thanks for the articles. Confirmed what Dr. Ruddy explained to me.

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Colleen Young, Connect Director | @colleenyoung | Jul 9, 2024
In reply to @dick61 "Thanks for the articles. Confirmed what Dr. Ruddy explained to me." + (show)
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Thanks for the articles. Confirmed what Dr. Ruddy explained to me.

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I'm a fan of Dr. Ruddy. Nice to get confirmation that the articles confirm her expertise. Thanks for letting me know.

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Arvind Natarajan | @malebreastcancer47 | Dec 17, 2025

Hello….I took 20 mg Tamoxifen for 1 year, and recently asked Mayo oncology to lower as I could not handle the side effects. Daily menopause, chills, fatigue, drowsiness, lack of any energy, depression, sleep issues, nutrition issues etc.
So far with 10 mg, taken every other day, life is much better. Still have daily drowsy but drink green tea. At night drink chamomile tea, which helps greatly to fight fatigue.

Due to my oncotype dx score of 34, I have to take Tamoxifen, vs stop taking. Its a good compromise.

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