MAC Treatment: Rifampin vs Clofazimine

Posted by wolfplanetzero @wolfplanetzero, Jul 28 1:54pm

In a recent scholarly article, the author, a pulmonologist from South Korea, argues that clofazimine might be a better choice than rifampin for treating MAC. He also mentions recent studies that showed that a two drug regimen of a macrolide plus ethambutol was as effective as the Big 3 regimen of a macrolide plus ethambutol and rifampin.
https://pmc.ncbi.nlm.nih.gov/articles/PMC12277505/
In the United States clofazimine is considered an investigational drug, so obtaining a prescription can take a bit of work. Another option might be to join a Phase 3 clinical trial of inhaled clofazimine, which is currently recruiting at multiple locations. Whatever your treatment plan consists of, I wish you the best of luck and smooth sailing.
https://www.icon-1study.com

Interested in more discussions like this? Go to the MAC & Bronchiectasis Support Group.

I have not started my treatment yet for MAC Abscessus I am interested in information.

REPLY
Profile picture for sofarsurvivor139 @sofarsurvivor139

I have not started my treatment yet for MAC Abscessus I am interested in information.

Jump to this post

Welcome to Mayo Connect and especially to our MAC & Bronchiectasis support group. Can you tell us a little about your diagnosis with M Abscessus and whether you are working with a doctor familiar with treating it, since it is a very rare infection.

REPLY
Please sign in or register to post a reply.