Tapering off Lyrica gave me panic, nausea, extreme anxiety

Posted by cdcc @cdcc, Nov 28, 2017

I have been taking Lyrica 150 mg two times a day for four years for trigeminal nerve neuralgia from shingles. Since I am now beginning to loose my teeth from this medication I decided to go off it. Folding my doctors withdrawal program I became very sick. Panic, extreme anxiety, nausea, could not eat and lost 17 pounds in 7 weeks, not good I’m tiny as it is. Ended in the ER for I’ve fluids, nausea medications. Back to the family doctor. He put me back on 50mg a day because he felt I needed a long withdrawal from the medications then also said you may have to go back on your full dosing which after all this suffering I am doing I don’t want to do that. I have even made an appoint with a psychiatrist to help with the anxiety although my family doctor gave me Ativan 0:5mg to take twice daily. I don’t even wan5 to go outside the house, haven’t driven in 7 weeks afraid my anxiety or panic will take over. Has anyone experienced these conditions with coming off this medication. Thank you

Interested in more discussions like this? Go to the Depression & Anxiety group.

@nancybomber

I have been on Lyrica for about 9 years. I started at 200mg 2x/ day for upper back and neck neuralgia.. about 7 years ago, after regular PT, Acupuncture and Osteopathic treatments, I was feeling better so I began decreasing my dose under the care of my very open minded FP Dr. I decreased it by 25mg once a day , once a week for a month. Then 2x per week once a day for a month etc. So basically it took me 14 months to get to 175mg 2x/ day. I felt like I was “ tricking my body into accepting a lower dose. What I noticed was that when I reached the month where I decreased it by 25mg 3x/ week once a day. I would start getting increase in my nerve pain. Usually after 1-2 weeks it would subside. If it did not, I would stay on that dose until it resolved. At this rate it has taken me 7 years to get down to 50mg 2x/ day. I am now working on getting down to 25 mg in the morning, I am at 25mg 3x/ week 50 mg 4X/ week in the morning and 50mg at night. Anyway. I have been feeling off and nauseated, so wondered if it is from the withdrawal. This would be the first time I am aware of having withdrawal affects except increase nerve pain in the past. I wondered if it might be because going from 50 mg to 25mg is a 50% decrease which is more of a decrease in the past and my body noticed it more. I also noticed when I got to the 50mg 2x/ day that I felt more clear minded and actually less anxious and did not have episodes of euphoria that I had had in the past. None of which I attributed to the Lyrica. I thought it was my mood disorder, that I’ve been in treatment for. I think the Lyrica May have exaggerated the mood disorder. I got excited that I had less of these feelings so went down faster than than the usual 25mg once a week for a month. So I did it for two weeks before going down another 25mg a week. That maybe why so feel nauseated. I am grateful, however for the Lyrica. If I had not been able to take it, I may have ended up on disability. It really helped my pain. I am glad to be almost off of it though. I hope you feel much better soon.

Jump to this post

I was in 300mg per day for six years and d3cided to come off it because I lost six teet( while takin* it and implants ar3 not cheap. It took me five months to come off it. I went into severe withdrawal panic, anxiety, agoraphobia, suicidal thoughts, severe nausea,loss of appetite an$ i list 38 lbs. I ended up in the ER with dehydration and severe nausea. They ch3cked with poison control to make sure the taper was correct which itwas but to fast sunc3 I took it for so long. What a nightmar3 I gav3 gone through. I’m ten months off now and I wan no pharmaceutical drugs in m6 system anymore. How this drug messed with my neurotransmitter which can take up to two years to repair itself. I hav3 a great friend whose husband is a doctor who to,d me to us3 as much CBD oil, CBD gummy’s as I need. Also to,d me to get GABA calm whic( you can buy in a health food store and let me tell you they are fantastic, I got the dissolvable ones. I feel so much better an$ i5 helps with h my severe anxiety. I also joined on FB Lyrica survivor group and tomy duror8s3 somany peopl3 ar3 going through what I am, the6 ar3 such a great support group. I do hope that what ever you choose to do, take your time don’t do cold turkey p. I even got a therapus5 because I was r3ady to commit suicide. This dru* I’d horrible to th3 human body sn$ how i5 takes it over. I’ve been told it’s worse to vpcine off of then heroin

REPLY

I have been on Lyrica for 4 months for neuropathic problems in my legs and feet. I was switched over from gabapentin. It had stopped being effective for me but I was not having any side effects from it at all and had been on it for 5 years. At first I was not feeling any side effects of the Lyrica but recently been feeling extremely depressed, anxious and at times, suicidal thoughts. It's not helping my neuropathy at all and the insomnia is getting worse. The worst part about this experience is that I have just moved to a new state without my husband I am enduring all this alone. I feel like I am going insane. I have attempted to slowly wean myself off this horrible drug without any help from a doctor because the health care system in the state I am living in is absolutely awful. It's almost impossible to get the doctor on the phone or even get through on the phone to get an appointment. The depression is crippling. The side effects getting worse. As it is I suffer from migraines and I have been waking up with horrible headaches, the fatigue is awful and I have no help around me. I had NO idea this drug was so horrible and would do so much damage. I am determined to grit this out to stop this God-awful drug but I'm not sure how much longer I can hang on without any help.

REPLY
@12pawz

I have been on Lyrica for 4 months for neuropathic problems in my legs and feet. I was switched over from gabapentin. It had stopped being effective for me but I was not having any side effects from it at all and had been on it for 5 years. At first I was not feeling any side effects of the Lyrica but recently been feeling extremely depressed, anxious and at times, suicidal thoughts. It's not helping my neuropathy at all and the insomnia is getting worse. The worst part about this experience is that I have just moved to a new state without my husband I am enduring all this alone. I feel like I am going insane. I have attempted to slowly wean myself off this horrible drug without any help from a doctor because the health care system in the state I am living in is absolutely awful. It's almost impossible to get the doctor on the phone or even get through on the phone to get an appointment. The depression is crippling. The side effects getting worse. As it is I suffer from migraines and I have been waking up with horrible headaches, the fatigue is awful and I have no help around me. I had NO idea this drug was so horrible and would do so much damage. I am determined to grit this out to stop this God-awful drug but I'm not sure how much longer I can hang on without any help.

Jump to this post

Hello @12pawz, Welcome to Mayo Clinic Connect. I'm glad you found us. I know it's not much help but you are not alone. Depression can be crippling. Will your doctor work with you to taper off of Lyrica? There is some information that may be helpful here but other members may be able to offer more or better suggestions:

Lyrica Withdrawal
https://www.recovery.org/lyrica/

Hoping you find some answers soon…

REPLY
@johnbishop

Hello @12pawz, Welcome to Mayo Clinic Connect. I'm glad you found us. I know it's not much help but you are not alone. Depression can be crippling. Will your doctor work with you to taper off of Lyrica? There is some information that may be helpful here but other members may be able to offer more or better suggestions:

Lyrica Withdrawal
https://www.recovery.org/lyrica/

Hoping you find some answers soon…

Jump to this post

Thank you for your reply and for the link, it is definitely an eye-opener. I am finding CBD oil to be helpful with the insomnia and the neuropathy as well and I am trying to schedule an appointment with the doctor but it takes forever. I think by the time that happens, I will have weaned myself off the drug and won't be in need of any help from her. The headaches have been awful too.

REPLY

I see I’m not the only one that goes through Lyrica withdrawals but I get them very bad, me and my fiancé almost broke up cause I got extreme aggravation moods, highly depressed, I withdrew from school for a few months I can’t sleep or eat I’m always hot or cold and I just finished my last script today so tomorrow I’m gonna be suffering so bad and I’m so scared of going through that again. Is there a suboxone version for Lyrica or something for the withdrawals cause I can’t go through this again. Last time was for 2 weeks I went through it and I need all the help I can get. I was on 1200 mgs a day the last time but this time I’m only on 600mgs a day is there a drug to take until the symptoms subside or how do I do this my doctor won’t give me anymore since I’m seeing a new doctor and he don’t believe in that stuff please help someone

REPLY
@jfanesi

I see I’m not the only one that goes through Lyrica withdrawals but I get them very bad, me and my fiancé almost broke up cause I got extreme aggravation moods, highly depressed, I withdrew from school for a few months I can’t sleep or eat I’m always hot or cold and I just finished my last script today so tomorrow I’m gonna be suffering so bad and I’m so scared of going through that again. Is there a suboxone version for Lyrica or something for the withdrawals cause I can’t go through this again. Last time was for 2 weeks I went through it and I need all the help I can get. I was on 1200 mgs a day the last time but this time I’m only on 600mgs a day is there a drug to take until the symptoms subside or how do I do this my doctor won’t give me anymore since I’m seeing a new doctor and he don’t believe in that stuff please help someone

Jump to this post

Hello @jfanesi, Welcome to Mayo Clinic Connect. Sorry you have to go through the withdrawal symptoms. I know it's not easy. There are other members here who I'm sure can offer some suggestions. I did find some information with suggestions that may be helpful here:

Lyrica (Pregabalin) Withdrawal And Detox
https://www.therecoveryvillage.com/lyrica-addiction/withdrawal-detox/#gref

I think the key is to taper off slowly. Are you able to talk to your doctor about a schedule for tapering off of lyrica?

REPLY
@johnbishop

Hello @jfanesi, Welcome to Mayo Clinic Connect. Sorry you have to go through the withdrawal symptoms. I know it's not easy. There are other members here who I'm sure can offer some suggestions. I did find some information with suggestions that may be helpful here:

Lyrica (Pregabalin) Withdrawal And Detox
https://www.therecoveryvillage.com/lyrica-addiction/withdrawal-detox/#gref

I think the key is to taper off slowly. Are you able to talk to your doctor about a schedule for tapering off of lyrica?

Jump to this post

No cause I moved across country and my doctor now don’t believe in Lyrica and those type of meds so I can’t taper off cause today was my last dosage

REPLY

This is probably not helpful, but it's my experience trying to taper of Lyrica (200mg once a day for fibromyalgia)…I wanted to get off Lyrica because I thought it was causing weight gain (like 5 pounds…silly of me). So my doctor said to just take it every other day, and then every three days, and then done. I was taking gabapentin as well, as needed. I had no physical symptoms, but I felt really anxious at the time because I had a lot of work stress, and I never connected it to the Lyrica. Then this happened: a sudden drop off the deep end of depression, two hospitalizations, weeks out of work on FMLA leave, four serious and nearly successful suicide attempts in two months. About 3 months in, I said to my best friend something about "at least I'm not getting fatter" and she gasped, dialed my psychiatrist (I was under strict supervision by friends at this point), who dialed my rheumatologist, who called in a prescription for Lyrica to the distant state where I was trying to convalesce. My best friend drove me to the pharmacy at a highly illegal speed and watched me (still protesting weight gain) take a capsule. The suicidal ideation was gone within 24 hours. The depression lifted to a manageable medium over the course of a week or so. The anxiety took quite a while to improve, but I think I was just born anxious. My psychiatrist and rheumie have agreed that I need to be on Lyrica for the foreseeable future, possibly for the rest of my life (I am only 33). This stuff changed me so dramatically that my brain was not willing to live without it. The advice I have for people weaning off is to pay attention to what your brain is telling you – is it telling you lies? – and remember that it's probably Lyrica withdrawal…and know if your body has had enough and you need to restart Lyrica and figure out another path.

REPLY

@eburning Wow so glad you had good friends That's awful what you went through I'm sorry hope your much better now Yes any meds can cause a dramatic change and a slow taper I'd the key for anyone Glad your better Take care

REPLY
@jfanesi

No cause I moved across country and my doctor now don’t believe in Lyrica and those type of meds so I can’t taper off cause today was my last dosage

Jump to this post

Focus on surviving. Your brain is doing awful things to you, but you can seize control back. Focus on self-care. Set reminders on your phone to eat…SOMETHING. Try to be out with your friends or family as much as possible, and if you can't, find places in public you can hang out during the day. Every time you feel something bad, remember: your brain is lying to you. Get your close people on board so they can recognize symptoms – this is not something to be ashamed of. Call in all the help you can get. Snuggle with your pets. I have found that benadryl helps with anxiety (and sleeping)(I am not a doctor and this should not be construed as medical advice). It's okay to be totally selfish right now – you would help your people through anything, and so will they if they understand the issues you're facing. There are a few alternatives to benzos for anxiety – beta blockers, antihistamines, etc. See if your doctor can prescribe some of that, and if he won't, just ask about OTC benadryl.

You can survive it. It's hard work, but it's so worth it.

REPLY
@eburning

This is probably not helpful, but it's my experience trying to taper of Lyrica (200mg once a day for fibromyalgia)…I wanted to get off Lyrica because I thought it was causing weight gain (like 5 pounds…silly of me). So my doctor said to just take it every other day, and then every three days, and then done. I was taking gabapentin as well, as needed. I had no physical symptoms, but I felt really anxious at the time because I had a lot of work stress, and I never connected it to the Lyrica. Then this happened: a sudden drop off the deep end of depression, two hospitalizations, weeks out of work on FMLA leave, four serious and nearly successful suicide attempts in two months. About 3 months in, I said to my best friend something about "at least I'm not getting fatter" and she gasped, dialed my psychiatrist (I was under strict supervision by friends at this point), who dialed my rheumatologist, who called in a prescription for Lyrica to the distant state where I was trying to convalesce. My best friend drove me to the pharmacy at a highly illegal speed and watched me (still protesting weight gain) take a capsule. The suicidal ideation was gone within 24 hours. The depression lifted to a manageable medium over the course of a week or so. The anxiety took quite a while to improve, but I think I was just born anxious. My psychiatrist and rheumie have agreed that I need to be on Lyrica for the foreseeable future, possibly for the rest of my life (I am only 33). This stuff changed me so dramatically that my brain was not willing to live without it. The advice I have for people weaning off is to pay attention to what your brain is telling you – is it telling you lies? – and remember that it's probably Lyrica withdrawal…and know if your body has had enough and you need to restart Lyrica and figure out another path.

Jump to this post

I’ll be off Lyrica for a year I. Another week. Withdrawal from this horrendous drug did a number on me. It’s worse then heroine withdrawal I’ve been to.d. It put me in a state of severe depression, anxiety, panic and agoraphobia. I ended up in the ER for dehydration and nausea. I wanted to commit suicide all the time, so I knew I needed a therapist, who. I’ve been seeing for a year now. She has helped me so much, even told me they have seen worse off then me coming off this drug. I found that hard to believe since I was so bad off. I don’t want any pharmaceutical drugs anymore. Im Getting better but still suffer with anxiety especially upon awaking. I wish you the best in what you are doing,

REPLY
@cdcc

I’ll be off Lyrica for a year I. Another week. Withdrawal from this horrendous drug did a number on me. It’s worse then heroine withdrawal I’ve been to.d. It put me in a state of severe depression, anxiety, panic and agoraphobia. I ended up in the ER for dehydration and nausea. I wanted to commit suicide all the time, so I knew I needed a therapist, who. I’ve been seeing for a year now. She has helped me so much, even told me they have seen worse off then me coming off this drug. I found that hard to believe since I was so bad off. I don’t want any pharmaceutical drugs anymore. Im Getting better but still suffer with anxiety especially upon awaking. I wish you the best in what you are doing,

Jump to this post

@cdcc That's awful sorry for what you went through Why does the Dr,s put us through these drugs oh yes money in there pockets Be your own advicate about your health research on the internet there,s alot of good information here Here,s some sites I use https:// http://www.WebMD.com type in the search box ,https://www drugs.com ,side effects ,interactions and what it's good for .https:// http://www.nih.gov I wish you well

REPLY
Please sign in or register to post a reply.
  Request Appointment