Lupron yeah or Lupron nay that is the question.

Run as fast as you can from Lupron or anything like it. These medicines are poison! You'll find in this blog that there are men who stopped Lupron as long as 7 years ago and are still experiencing horrific side effects. I convinced my care team to stop these injections after 9 months. Although some of the side effects have waned, I'm now facing osteoporosis and they (of course) want me to take other drugs. I few weeks ago I leaned over the soft arm of our sofa and broke a rib. Good luck and God speed.

This is not good advice. I’ve been on ADT for nine years, It has kept me alive along with an ARSI (first Zytiga now Nubeqa). I’ve had four reoccurrences, but that’s kept it under control Even though I have the genetic problem of BRCA2, Which prevents my DNA from correcting errors.

I’ve been on bone straighteners for about eight years. If you go on ADT, you are supposed to go on bone strengtheners right away, According to a bone specialist, who gave a talk within the last year about ADT and bones.

Stopping ADT too soon can result in a shortened progression free survival. Not everybody needs it for a long time. If you have a high Gleason score, it can Extend your life significantly.

I do t believe this is the case for everyone. My husband was57 when he was diagnosed with prostate cancer, surgically removed, no chemo or radiation at the time. Lupron injections kept the cancer cells from multiplying for 30 years. He just passed away at the age of 88. I feel so fortunate that his doctors felt the need for lupron was greater than the annoying side effects it created.

I think you meant to say that you DO NOT believe this is the case for everyone....

Sorry for your loss, was he on Lupron the entire 30 years? Wow!

Since we are all different and our cancer is unique, our treatments need to fit each individual’s cancer. That said, despite the numerous and awful side effects of Lupron, it does work for most people and does stop or slow the progression of prostate cancer. nine years ago I had prostatectomy due to a very small amount of Gleason 3+5 cancer near the capsule. After three years, my PSA became detectable and was going up. They gave me two months of daily radiation and six months of Lupron. The side effects of the Lupron were minimal and testosterone returned to 400 within three months with no residual side effects. After a couple of years, my PSA started to increase again and my PSMA PET scan showed a single lesion (oligometastic cancer) on my sacrum. It was radiated and I was put on Lupron and Abiraterone/Prednisone. For the next three years I had undetectable PSA and clean PSMA PET scans. Since the side effects were numerous and awful, I elected to go off ADT, at least until my PSA showed cancer again. That was ten months ago and I still have no signs of cancer. Unfortunately, I still have most of the side effects although my testosterone is slowly returning. Would I take Lupron again? Absolutely! I am living a wonderful , active life instead of dying of cancer.

So far I have only had one Lupron shot with Abiraterone/Presidone and am due for another shot next month. Before starting with Lupron my PSA was 0.03. I had 24 radiation treatments four years ago (diagnosed with a Gleason 9) and now the cancer has metastasized to my bones again. One spot on my spine which came back after it was radiated a year ago, and a tiny spot on my pelvis. I never felt any discomfort or pain until I was put on Lupron. Now I am in constant pain every minute of every day and I can barely function. I'm afraid another shot of Lupron will put me in a wheelchair for the rest of my life.

It is established standard of care to be on Abiraterone and prednisone and Lupron. They kept my husband's Stage 4 MCRPC suppressed for over three years. HOWEVER, there are other medications you can take instead of Lupron which have the same benefit if its side effects are terrible for you. Please ask your oncologist or whoever prescribed Lupron for an alternative. You don't need to be miserable or take chances with recurrence.

The problem with the pain is probably not just Lupron. If you started Lupron without having Biclutamide (Casodex) for the first two weeks, then you will get flares that can cause pain. That would be a mistake made by your doctor.

Once you’ve passed the first shot, the flares pretty much stop. It’s more likely that the pain is bone pain from metastasis. This is something you really need to discuss with your doctor to find out what it could be. Adding an ARSI might benefit you in more than one way, You could reduce the chance of early castrate resistance, And it would be more effective in reducing bone metastasis, and pain.

Lupron can reduce your Bone density and that can cause problems. At a recent conference, a bone doctor talked about the fact that anybody on ADT should be on bone strengtheners, which can help with Increasing bone density. I was on Fosamax For the first six years, I was on Lupron and then switched over to Zometa. It is kept my bones strong and I’ve never had a problem with pain even though it was on Lupron for over six years and now Orgovyx.

Yes he was, every three months like clockwork! He did have relapses but nothing that couldn’t be handled by radiation. At age 88, the cancer took over and nothing was working. But, he was a young 88, and we both felt blessed that we had those extra 30 years.