Lung Nodule, D-Dimer elevation and ANA +VE

Posted by sheker @sheker, Oct 10, 2018

Lung Nodule, D-Dimer elevation and ANA +VE:

Do I have LUPUS?
In June during my India trip left side Ribs pain started when breathing.I returned to US on July 5th and next day I visited primary care, he ordered CMP and X-RAY both are normal.nothing shown in the X-RAY.After 2 weeks I visited primary care again, then he checked EKG, it was normal.In my 3rd visit Primary care ordered bone scan which gave some clue about pleural effusion.After that i visited Pulomonologist, he checked ANA which came +VE,D-Dimer elevated(high).Then Pulomonologist ordered CT scan in which identified a patchy nodule, by this time pain was severe, lots of burping and incomplete yawning. For small burping and yawing back was hurting a lot.

After nodule identified in the lung, doctor put me on LEVOFLOXACIN for one week then pain got controlled.I finished medication on 09/27, after 10 days ribs pain started again. I am 47 yrs old,hypothyroid patient,previously i was diagnosed with Fibromyalgia (since 2010).These things are scaring me and making me sleepless. Need advise.

Chest X-Ray report (07/12/2018)
"PA and lateral chest images. Heart size and contour are normal. Lungs are clear with normal pulmonary vascularity. No pleural effusion, hilar or
mediastinal prominence is evident"

Bone scan report (09/04/2018)
“Mild asymmetric increased uptake in the left posterior hemithorax. Tracer is distribution is otherwise un remarkable”

CT Scan report (09/18/2018)
"As per regular modules identified within the superior segment left lower lobe measuring together an area of 2.4×2.2 cm.Possibly post infectious. Trace loculated left pleural effusion."

ANA TEST and other Lab tests (09/12/2018)
1.ANA SCR, IFA, W/REFL TITER/PATTERN/SJOGREN'S PANEL 1
–SJOGREN'S ANTIBODY (SS-A) –NAGATIVE
— RHEUMATOID FACTOR –NAGATIVE
–SJOGREN'S ANTIBODY (SS-B) –NAGATIVE
–ANA SCREEN, IFA, W/REFL TITER AND PATTERN — POSITIVE
2.ANA SCR,IFA W/REFL TITER/PATTERN/SYSTEMIC SCLEROSIS PANEL 1
— ANA SCREEN, IFA –POSITIVE
— SCL-70 ANTIBODY–NAGATIVE
–CENTROMERE B ANTIBODY–NAGATIVE
–RNA POLYMERASE III AB–NAGATIVE
3.D-DIMER, QUANTITATIVE — 1.35 (should be less than 0.5)
4.ANA SCR,IFA W/REFL TITER/ PATTERN/LUPUS PNL 1
--ANA SCREEN, IFA-- POSITIVE
5.ANTINUCLEAR ANTIBODIES TITER AND PATTERN
--ANA PATTERN --Nucleolar
--ANA TITER=1.40 ( should be

Interested in more discussions like this? Go to the Autoimmune Diseases Support Group.

@nikohl7

That’s great news! Though I’m sure it’s frustrating since it doesn’t give you any further clues as to what the problem is. Do you meet any of the lupus criteria? Usually 3-4(depending on what state you are in and insurance standards) is a pretty good indication it could be lupus. Though I have no heard of a hemothorax being caused by lupus, have you had any infectious disease testing?

Jump to this post

@nikohl7
Previously when I mentioned to my physician about infections, he said he don't expect infections.
What are the lab tests require to test infectious disease?

REPLY

Nicohl,

In 2nd CT (After 6 week) nodule size reduced, then Dr orders 3 rd CT after 3 months, in 3rd CT size increased little , so Radiologist mentioned like “due to persistent nodule it is very difficult to exclude malignancy and immediate biopsy is suggested”.
Doctor sent me for biopsy after two weeks, before they start biopsy ordered latest CT to locate the nodelu position, in CT again size got resuced.So they didn’t continue with biopsy as size reduced.
Ribs pain is always there.no clue at this time.

REPLY
@sheker

Nicohl,

In 2nd CT (After 6 week) nodule size reduced, then Dr orders 3 rd CT after 3 months, in 3rd CT size increased little , so Radiologist mentioned like “due to persistent nodule it is very difficult to exclude malignancy and immediate biopsy is suggested”.
Doctor sent me for biopsy after two weeks, before they start biopsy ordered latest CT to locate the nodelu position, in CT again size got resuced.So they didn’t continue with biopsy as size reduced.
Ribs pain is always there.no clue at this time.

Jump to this post

I have had very similar symptoms with rib pain and fluctuation in lung nodule increase/decrease. I had a bunch going on at that time. Collapsed lung that would not heal,and a pleurodesis treatment that went wrong. The pain in my ribs was something I never felt before. My doctors couldn't figure out why I was in so much pain. My pulmonologist finally put me on colchicine and it worked. I was only on it a short while. There are a ton of natural anti-inflammatorys you could try also.

REPLY
@fracturedd

I have had very similar symptoms with rib pain and fluctuation in lung nodule increase/decrease. I had a bunch going on at that time. Collapsed lung that would not heal,and a pleurodesis treatment that went wrong. The pain in my ribs was something I never felt before. My doctors couldn't figure out why I was in so much pain. My pulmonologist finally put me on colchicine and it worked. I was only on it a short while. There are a ton of natural anti-inflammatorys you could try also.

Jump to this post

I forgot to add my pulmonologist said the fluctuation in the lung nodule was due to inflammation. Hence the reason the colchicine helped in my case.

REPLY
Please sign in or register to post a reply.