Lowering platelet level with food

Posted by panamsandy @panamsandy, May 21, 2025

Is there a way of lowering platelet levels with food? I've been reading that certain foods can help. Cucumber, radish, cherries, blueberies, etc. and supplements like Ginko Biloba and Ginsing. I also read that red wine and dark chocolate help (I hope that one is true!! LOL)

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I'm about to try cranberry juice. Unsweetened cranberry juice has been used to lower platelet count. I discussed this with my hematologist and he says to go ahead and try it. My purpose is to replace Hydroxyurea, which is destroying some of my red blood cells, making me anemic.

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Profile picture for Lori, Volunteer Mentor @loribmt

Hi @panamsandy, There are diets posted online to potentially lower platelets by reducing inflammation in the body. But understanding the reasons behind elevated platelet counts is essential for determining effective strategies for reduction. In your case, if you have elevated platelets due to a genetic mutation such as JAK2, that is the driving force behind the proliferation of platelets in your body. So, from my understanding, diet alone won’t impact the platelet level and it won’t reverse the mutation.

Supplements need to be run past your hematologist first. Because they are often unregulated, testing is vague when it comes to combining with certain blood cancers or the medications used to treat them. Some of the supplements can act as blood thinners, or damage the liver or kidneys, or interfere with the efficacy of a medication.
Ha, but gurl, red wine and dark chocolate? Sign me up! LOL. Alas, right now I can’t have either one. But basically, eat healthy with foods rich in antioxidants/anti inflammatory properties like whose you mentioned. Following the Mediterranean diet is a good base because it tends to be whole, clean foods, no processed items, healthy fats and anti-inflammatory.
Have you started HU yet or just trying to find a way around it? Are you able to take baby aspirin?

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@loribmt In my case, I don't have the JAK2 mutation. My mutation is the CALR Exon 9, and yes, this is what is driving my high platelet count, but there are foods that can change platelet count by either elevating it or reducing it. I've experienced some of those that raise platelet count and some of them (all dairy, green leafy vegetables, basically most of the foods recommended by doctors and nutritionists for a "balanced diet"). Ground beef, which has been a staple of my paleo diet since 2007, neither raises nor reduces my platelet count. It was my paleo diet that eliminated my Type 2 Diabetes within 5 months of starting the diet. I have had four doctors who tell me I have kidney disease, citing the protein load on my kidneys. Despite the presence of protein in my clear, light yellow urine, and an eGFR that the fourth doctor says is "wavering" between 3A and 3B, I still don't have a single symptom of kidney disease since it was first diagnosed in 2009. I don't need dialysis, either, and I feel fine. But, getting back to food and platelet count, I have read that unsweetened cranberry juice does lower platelet count and I'll be starting my experiment with that in June. Meanwhile, I will also be trying ginger (the chewable form) and ginger oil (for the rashes) in June. I didn't mention that, in 2024, doctor number four congratulated me on the fact that my eGFR had dropped from 3A to 2, where it had begun in 2009. No explanation, though, for how that happened. At the end of 2023, I quit eating fruit because of the sugar content and this resulted in my weight dropping from the mid 160s to the low 150s by this time.

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A side note, here, but is anyone experiencing interference with their brower when searching for information on using ginger to control platelet count? I did a search for that topic and my browser was immediately redirected to an ad for a VPN, then to something about TikTok and I never was able to see any pages on ginger and platelet count. Not to sound to "conspiratorial," but I have read that hackers are now using AI to highjack browsers.

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Profile picture for garyr443 @garyr443

I'm about to try cranberry juice. Unsweetened cranberry juice has been used to lower platelet count. I discussed this with my hematologist and he says to go ahead and try it. My purpose is to replace Hydroxyurea, which is destroying some of my red blood cells, making me anemic.

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@garyr443
I also read quinine in tonic water lowers platlets. My new mocktail with lime!

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Yes! I have been seeing references to quinine, especially in articles written for people with thrombocytopenia. It's one of the things they avoid, since their condition is the opposite of thrombocythemia. I have had very little luck in finding articles written for people with thrombocythemia, but these articles for the opposite condition are all over the internet. It doesn't matter what I'm searching for, I keep getting articles on raising platelet count, instead of lowering it. To these people with a low platelet count, raising platelet count is a good thing. So, since that's what I keep finding in my searches, I began reading those articles to see what foods to avoid and which foods to eat. I just have to do the opposite of whatever they recommend.

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Profile picture for susi1950 @susi1950

@garyr443
I also read quinine in tonic water lowers platlets. My new mocktail with lime!

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@susi1950 One thing I just thought of: I have discovered that a particular website (wellkr .com) will hijack your browser, so DON'T go there for anything!

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Profile picture for susi1950 @susi1950

@garyr443
I also read quinine in tonic water lowers platlets. My new mocktail with lime!

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@susi1950 Well, darn! I just read that people with kidney disease should not consume quinine. Oh, well, between the cranberry juice and the ginger, I think I've got the platelet lowering covered anyway.

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