Any thoughts on these test ?
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Hello @adah, welcome to Connect. I have no medical training or background but have read that if your immune system makes low levels of antibodies, you may have a greater chance of developing repeated infections. There are some good explanations of the tests here:
University of Michigan – Immunoglobulins: Test Overview
Blood Tests Explained: Immunoglobulins (PDF)
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Just wanted to mention a warning for all. Last Thursday was my birthday, so I got off my good diet by eating large portions of 2 very, very rich birthday cakes and drinking wine. After being of prednisone for over 2 weeks, had to take some this morning. I have PMR and the worst culprit for all inflammatory conditions is SUGAR.
@adah, May I ask why you are asking about IgA IgG and IgM antibodies? Are you and your doctor investigating a particular diagnosis?
Yes the dr is looking to see if my relative has cirrhosis or an autoimmune disorder
I have very low levels of IgG and was diagnosed with Common Variable Immune Disorder (CVID). I have been receiving IgG infusions for about 10 years now. For many years they worked very well and symptoms were greatly reduced. Unfortunately, for the past two years, my symptoms have increased. I do not have the most typical symptoms of chronic/frequent infections but rather less common digestive problem of daily episodes of vomiting and diarrhea. I would like to hear from others with CVID and learn from them what has helped and of course share what I have learned. My IgA is also low but I was told that it is of no concern as some people have no IgA.
@mightmouse — I'm tagging @ldestella @xfirerose and @cbdonlon who have discussed CVID in other discussion to see if they are able to offer any suggestions or information for you on CVID and what has helped.
Immunglobulin G is infused via IV into your blood stream. Mine is done at a cancer treatment center where people receive chemotherapy IV infusions. IgG is part of your immune system. It is a blood product. It has made a huge difference in my life. I use to have daily episodes of cramping, vomiting and diarrhea lasingt 3 to 4 hours. IgG infusions have very greatly reduced my symptoms. There are medical articles on the internet which can better inform you about IgG and CVID..
Google Iga and celiac. Go gluten free. I was diagnosed with celiac and discovered my IGA levels were so low. Actually zero. If they test for celiac and you come up negative. It is because the use the IGA in your blood. If your levels are so low. Then you will have a false negative for celiac.
Hello @jean9v, Welcome to Connect. Thank you for sharing this information. I thought I would share a reference on the topic since new members are not able to post links for a short period of time after joining Connect.
"Is IgA high or low in celiac disease?
Immunoglobulin A (IgA) deficiency is 10 to 15 times more common in patients with celiac disease (CD) than in healthy subjects. Serological tests have become the preferred methods of diagnosing CD in both symptomatic and asymptomatic patients."
— Celiac Disease and Immunoglobulin A Deficiency – NCBI: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC130112/
Do you mind sharing what brought you to Connect. Were you looking for something specific?
I was looking for any answers regarding CVID and vaccines lasting long or even taking when you have zero IGA.
Hello just curious if anyone has a similar medical profile. My igg's are dropping. Dx with sjogrens, SFN, dysautonomia, and now crohns. Immunologist says not a true CVID because of my lack of UR infections. Sure have gut stuff tho. Have low igg and igm and now my iga is also below the cut-off. Ty
Hello @lilymol. I found a discussion with members who have discussed this very topic so you will notice that I have moved your post here: https://connect.mayoclinic.org/discussion/low-levels-of-igg-iga-igm/
I did this so you can review what has been shared in the discussion already if you'd like and also so you may connect with members such as @jean9v.
What is your Immunologist suggesting for next steps?
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